DRUG NAME: Cyclophosphamide
presence of left ventricular dysfunction (ejection fraction less than 50%). 18. The mechanism may involve direct injury to the endothelium by phosphoramide mustard, an active metabolite of cyclophosphamide. 18,19. Unlike anthracyclines, cyclophosphamide-induced cardiotoxicity does not appear to be cumulative. 4,18,20. In contrast to
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