Importance, Objectives & Factors Affecting Dissolution ...
3) PARTICLE SIZE There is a direct relationship between surface area of drug and its dissolution rate. Since, surface area increases with decrease in particle size, higher dissolution rates may be achieved through reduction of particle size.
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1. Types or Techniques Probability Sampling
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dissolutiontech.comIn general, dissolution tests are useful for (1) assessing the characteristics of the active pharmaceutical ingredient (API) such as the particle size and the crystal form; (2) guiding development of new formulations; (3) assisting in proper formulation selection (selection of excipients) and optimizing the manufacturing process (e.g., compression