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Importance, Objectives & Factors Affecting Dissolution ...

Importance, Objectives & Factors Affecting Dissolution ...

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copagel (low viscosity grade of Na CMC) added before granulation decreased dissolution rate but if added after did not had any effect on dissolution rate. Microcrystalline cellulose is a very good disintegrating agent but at high compression force, it may retard drug dissolution.

  Dissolution, Compression, Granulation

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