PHARMACEUTICAL PACKAGING, COMPONENT AND …
Plastic containers also affect the physical properties of the product. For example, when water-in-oil emulsion is stored in a hydrophobic plastic bottle, there is a tendency for the oil phase to migrate & diffuse into the plastic. Permeation may also affect the shelf-life of a drug. 2. Leaching:
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1. Types or Techniques Probability Sampling
pharmaquest.weebly.comPHARMAQUEST (c) This method maintains the procedure of the finding evaluate the reliability of the sample. Disadvantages (a) This technique of sampling cannot be used for a large sample.It is applicable only for small sample. (b) This technique is time consuming, costly, and requires more competition.(c) Its planning and administration is more complicated.
FORMULATION AND EVALUATION OF VARIOUS …
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RESEARCH METHODOLOGY Methods and tools use in …
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Importance, Objectives & Factors Affecting Dissolution ...
pharmaquest.weebly.comThe processes involved in dissolution of solid dosage forms: ... Micronization of hydrophobic powders can lead to aggregation and floatation when powder is dispersed into dissolution medium. So, mere increase in S.A. of drug does not ... resulting in imparting hydrophilic character to granules & thus increase in effective surface area & rate of ...
ORDER OF REACTION - PharmaQuesT
pharmaquest.weebly.comWhen the reaction rate is independent of concentration of the reacting substance, it depends on the zero power of the reactant and therefore is zero order reaction. In this type of reaction, the limiting factor is something other than concentration, for example, solubility or absorption of light in certain photochemical reactions.
PRODUCTION PLANNING AND PRODUCTION CONTROL
pharmaquest.weebly.comThe main objective of scheduling is to arrange the work of the production in ... 2. Network analysis/ technique(CPM & PERT) 3. WORK BREAKDOWN STRUCTURE 4. MOTION STUDY (METHOD STUDY) 5. ... an American engineer and social scientist. Frequently used in project management, a Gantt chart provides a graphical illustration of a schedule that helps ...
INTRODUCTION & APPLICATION OF SOLUBILITY & …
pharmaquest.weebly.com3. Solubility of solids in liquids 1.Solubility of gases in liquids Pharmaceutical solution of gases includes hydrochloric acid, ammonia water, and effervescent preparation containing carbon dioxide (Aerosol) that are dissolved and maintained in solution under positive pressure. The solubility of such system depends primarily on the pressure ...
FACTORS AFFECTING DRUG ABSORPTION - PharmaQuesT
pharmaquest.weebly.com(1) Membrane physiology A. Nature of cell membrane B. Transport processes (2) Gastero-Intestinal motility A. Gastric emptying rate B. Intestinal motility C. Drug stability in GIT D. pH of GIT E. Surface area of GIT F. Intestinal transit G. Blood flow to GIT. H. Effect of food
Regulatory Requirements Related to Stability Testing
pharmaquest.weebly.comKinetic Mean Temperature (Virtual temperature) 21°C 26°C 31°C 31°C . Mean Annual Relative Humidity 45% 60% 40% 70% REQUIREMENT OF TEMPERATURE DEPENDED ON TYPE OF TESTING TYPE OF STUDY TEMPERATURE RELATIVE HUMIDITY TIME DURATION Long term 25°C ± 2°C /60% RH ± 5% RH 12 months ...
Stability:- Basic Concepts and Objectives
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