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Protecting Groups (PG) - ETH Z

Protecting Groups (PG) - ETH Z

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Amino Acids: Serine, Threonine, Hydroxyproline, Tyrosine Other protecting tgroups: Bn and Bu Hydroxyl PGs Introduction TBDMS‐Cl Allyl ONB‐Br Removal TBAF, 35% TFA Pd(PPh 3) 4, scavengers Photolytic cleavage (320 nm) Stable Basic conditions Basic and Acidic Conditions Acidic and mild basic conditions Orthogonal Fmoc Boc, Fmoc, ZFmoc, Boc

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