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Sample Size Calculations for Randomized Controlled Trials

Sample Size Calculations for Randomized Controlled Trials

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calculating sample size, one would use a standard formula for time to failure and select as the candidate sample size the larger of the sizes required to achieve the desired power— for example, 80 percent—for each of the two endpoints. Suppose that sample size is 1,500 per group for hospital-ization and 2,500 for mortality. Having ...

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