ZF 1 Zambia National Formulary ZNF 03 - Ministry …

1 1 ZNFZNF032013 Zambia National FormularyRecommendation CitationZambia National Formulary Committee (2011) Zambia National Formulary 2011 2013032013 Zambia National FormularyZNF45 ZNFF orewordThe Zambia National Formulary (ZNF) is an integral component of the Zambia National Medicines Policy that is aimed at making available and accessible essential medicines of proven efficacy, safety and quality at affordable cost. The ZNF is a major strategy in promo-tion of rational use of edition of the ZNF has maintained the basic objectives and organization of the previ-ous edition. This edition emphasizes the need for evidence based treatments as derived from the Standard treatment guidelines (STDs). The development of this document is consulta-tive and participatory. The ZNF is a very dynamic document that needs regular review and update to make it truly relevant in meeting health needs of our Zambia National Formulary Committee (ZNFC) responsible for development and dis-semination of this document welcomes the active participation of all stakeholders to achieve our goal of promoting rational use of medicines in the delivery of quality health Peter MwabaPermanent SecretaryMinistry of HealthZNF6 PrefaceThe publication of Zambia National Formulary (ZNF) is yet another milestone of Zambia National Formulary committee activities.

2 The ZNF is authentic publication that reflects the priorities of the Zambia National Medicines Policy and is accepted as a reliable guide by health workers for the purpose of prescription of ZNF is accepted by government as a standard reference document and as an authority as far as the Formulary is Formulary contains information about essential and rational medicines available on the Zambia Essential Medicines List (ZEML). The indications, contraindications, drug interactions, side effects and dosages are is hoped that this publication will equip the health worker both in public and private sectors with enough information for rational prescribing, help to keep cost of medication reasonable and affordable and reduce adverse Ministry of Health will update this document on biennually basis to keep it relevant for G. SyakantuDirector, Clinical Care & Diagnostics Services 7 ZNFA cknowledgementThe Zambia National Formulary Committee is grateful to the Ministry of Health for the support given to the Committee during the preparation of this edition of the Formulary .

3 The Committee would also like to thank WHO, MSH RPM Plus and Clinton Foundation for financial and technical support towards the preparation of the Formulary . Some advice and contributions were also received from various health professionals from various Committee would also like to thank Mrs. Mildred Mulenga, Mr Chikuta Mbewe, Mrs Bernice Mwale, Mr Luke Alutuli, Mr George Kadimba, Mr Maxwell kasonde, Mrs Florence Chindalo from ZNFC Secretariat for their support and Mrs Mary N Mupeta for typesetting and computerising the text for print-ing. We would like to acknowledge UNICEF support for typesetting services to the 6 ACKNOWLEDGEMENT 7 Zambia National Formulary COMMITTEE 9 PRESCRIPTION WRITING 11 DRUGS STABILITY 4 DRUG STORAGE INFORMATION 6 VEN CLASSIFICATION 81.

4 Drugs used in anaesthesia 162. Drugs Acting on the Gastrol-Intestinal System 193. Drugs Acting on the Central nervous System 264. Drugs used in treatment in the infections 405. Drugs Acting on the Endocrine system 69 6. Drugs used in the treatment of disease of the respiratory system 80 7. Drugs used in the treatment of disease of the cardiovascular system 888. Drugs used in treatment of malignant disease 959. Drugs Acting on the eye 9910. Blood 10111. Nutrition 10512. Drugs Acting on the skin 11113. Drugs used in the treatment of the ear, Norse and Oropharynx 11714.

5 Drugs used in the treatment of musculoskeletal disorders 12315. Immunological products and vaccines 13016. General treatment of poisoning 151 APPENDIX 1 153 APPENDIX 2 158 APPENDIX 3 166 APPENDIX 4 172 APPENDIX 5 173 APPENDIX 6 174 APPENDIX 7 178 DRUG INDEX 1819 ZNFZAMBIA National Formulary COMMITTEE 2011 - 20131. Professor Chifumbe Chintu, Haemato-oncologist, UTH2. Dr John Musuku, Consultant Paediatric Cardiologist 3. Dr Kennedy Lishimpi, Oncologist4. Dr Maureen Chisembele, Obstetrician/Gynaecologist, UTH5. Dr Robert Zulu, General Surgeon 6. Dr Kalinichenko, Cardiologist, UTH7. Dr Izukanji Sikazwe, Infectious Disease Specialist, MoH8. Dr Crispin Moyo, HIV Medicine Specialist, MoH9.

6 Dr Gloria Munthali, Clinical Care Specialist, MoH10. Dr A Chomba, Dermatologist, UTH11. Dr Jospeh Wapabeti, Psychiatrist, Chainama Hills Hospital12. Dr Nason Lambwe, Consultant Physician, UTH13. Dr Lawrence Siyamuyoba, Internal Medicine Specialist14. Dr Jenipher Chisanga, General Medical Officer15. Dr L T Mungo, Lecturer, Pharmacy Department, UNZA School of Medicine16. Mrs Loyce Lishimpi, Pharmacist17. Mr Oliver Hazemba, Pharmacist, Management Sciences for Health (MSH)18. Mr Enock Chikatula, Pharmacist, UTH19. Dr Aggrey Mweemba, Renal Specialist20. Dr Gardner Syakantu, Director, Clinical Care & Diagnostics, MoH21. Ms Esnat Mwape, Director General, Pharmaceutical Regulatory Authority (PRA)22. Mr Patrick Banda, Senior Planner, Planning & Budgeting, MoH23. Dr Mary Miyanda, Ophthalmologist, MoH24. Dr Mutale Nsakashalo, Non-Communicable Diseases (NCDs) Specialist 25. Dr Nathan Kapata, TB Specialist26.

7 Mrs Pamela Kauseni, Economist, MoFND27. Mrs Anne Zulu, Director of standards , MSL28. Mrs Bernice Mwale, Director, Product Registration, PRA 29. Mrs Mildred Mulenga, Principal Pharmacist, Principal Pharmacist, Rational Use of Medicines, MoH30. Mr Chikuta Mbewe, Deputy Director, Pharmaceutical Services 31. Mr Luke Alutuli, Principal pharmacist, Logistics Management32. Mrs Florence Chindalo, Secretary, DCCDs, MoHOther Technical Reviewers 1. Dr F Simenda, Psychiatrist2. Mr George Kadimba, Lusaka District Phar-macist3. Ms Dorothy Samalesu, EN/Counselor, MoH4. Mr Maxwell Kasonde, Pharmacist Lusaka DHMT5. Mr Billy Mweetwa, Pharmacist, WHO6. Dr Albert Mwango, National Antiretroviral Programme Coordinator, MoH7. Ms Fales Mwamba, Dip MLT, Bsc (Hon) MLS, MoHEditor Mr Spencer Banda, BA UNZA, Med. (Man)Design and printNew Horizon Printing PressSecretariat1. Mrs Bernice Mwale, Director, Product Registration, PRA 2.

8 Mrs Mildred Mulenga, Principal Pharmacist, Principal Pharmacist, Rational Use of Medicines, MoH3. Mr Luke Alutuli, Principal pharmacist, Logistics Management4. Mrs Florence Chindalo, Secretary, DCCDs, MoH5. Mr Katongo ChikwandaZNF10 The fifth edition of the Zambia National Formulary seeks to provide a list of drugs suitable for use in Zambia together with essential information about their drug selection has been based on the proven efficacy and potential of InformationThe main text consists of classified notes and preparations. These have been divided into chapters according to a particular system of the body or an aspect of medical are further divided into sections which were necessary, have introductory notes for health care providers who include doctors, pharmacists, nurses and other heath professionals. This information is intended to facilitate the selection of appropriate monographs and details of relevant preparations follow the an Prescribing and Prescription WritingThis part of the Formulary contains information on prescription writing, prescribing for children and the elderly, advice on promoting compliance, drug stability, storage conditions and the VEN classification system for setting procurement and stocking prioritiesDrug Name Appears under approved name or non-proprietary title on the International Non-proprietary name (INN)Presentation Indicates the dosage form in which the drug is Gives details of the indications for the use of the drug Caution Highlights precaution required.

9 May include counselling of patient on how to take Indications Any contra indications to the use of the drug are Effects Gives details of common and more serious side treatment of Poisoning This chapter deals with the management of all cases of poisoning or suspected poisoning when first seen in the home through referral to a health And IndexesThe appendixes include information on immunisation schedules, drug interactions, haematological and clinical chemistry reference values for children, adults and during pregnancy, thyroid and reproductive hormones reference levels, additives to intravenous ( ) fluids and drugs in special section on patients leaflets and instructions give information on how to administer and use nasal drops, aerosols vaginal creams, ointments and gels, pessaries, suppositories, ear drops, eye drops and ointments.

10 This section follows the indexes lists the drugs in alphabetical order by approved name or Control and Drug AvailabilityPrescriber categories are not indicated in the text because it is expected that the drug availability will be controlled by:i. Drugs and therapeutic committees actively defining policies for prescribing within an institution or The range of availability of drugs in any institution being restricted according to the level of institution and to the categories of staff are advised to follow rational prescribing habits which emphasise the priority use of essential and economic treatment of DrugsBecause of constant price fluctuations it is impossible to include specific prices for drugs. However, your pharmacy staff will be able to give up to date information for your guidance.