Biotransformation Phase I And Phase

2章 药物代谢动力学 - ahmu.edu.cn

Phase I 药物 结合 药物 无活性 活性↑或↓ 药物 亲脂 亲水 排 泄 氧化、还原、水解引入或 脱去基团(-OH、-CH 3、-NH 2、-SH) Phase II 结合 结合 内源性葡萄糖苷酸、硫酸 、醋酸与药物或I期反应代 谢物结合 代谢步骤和方式 3. 代谢(metabolism, 生物转化, Biotransformation)

  Phases, Biotransformation

Biotransformation: Phase I and Phase II Metabolism

Biotransformation: Phase I and Phase II Metabolism • Xenobiotics: Xenobiotics are unwanted chemicals in the environment and the diet that the body is exposed to. Polar xenobiotics are easily eliminated by the body through urine, sweat, etc. However, lipophilic xenobiotics require a …

  Phases, Biotransformation, Phase i and phase

Biotransformation of drugs (Drug metabolism )

Biotransformation of drugs takes place in two steps: first phase - functionalization reactions the molecule introduces a new functional group, usually polar (-COOH,-OH,-NH2) the polar group can serve as a reaction point for the second reaction phase second phase - conjugation reactions

  Phases, Drug, Metabolism, Biotransformation, Drug metabolism, Biotransformation of drugs

BREVET PROFESSIONNEL PRÉPARATEUR EN ... - CFA Pharmacie

4.8 Citer l’organe principal impliqué dans les réactions de biotransformation. 4.9 Indiquer le terme général correspondant à la molécule obtenue par biotransformation. 4.10 Citer les deux voies principales d’éli mination des médicaments. 4.11 Indiquer l’autre classe pharmacologiqueégalement utilisée comme antisécrétoire

  Biotransformation

Linear Polydimethylsiloxanes CAS No. 63148-62-9 (Second ...

2.3.3 Sorption to solid-phase organic matter 11 2.4 Conversion factors 13 2.5 Analytical methods 13 2.5.1 General considerations 13 2.5.2 Extraction procedures 14 2.5.3 Conversion of analytical results to PDMS 15 2.6 Summary and evaluation 16 3. PRODUCTION, STORAGE AND HANDLING, TRANSP ORT AND USE 17 3.1 Production 17 3.2 Storage and handling 17

  Phases, Linear, 48316, 63148 62, Polydimethylsiloxane, Linear polydimethylsiloxanes cas no

Skript zum Praktikum „Arzneimittelanalytik“ im 8 ...

Skript zum Praktikum „Arzneimittelanalytik“ im 8. Fachsemester Pharmazie Seite 5 Seite 5 zu Acetylsalicylsäure Gehalt: 1,000g Substanz wird in einem Erlenmeyerkolben in 10 ml EtOH 96% R gelöst.Nach Zusatz von 50,0 ml NaOH-Lösung (0,5 mol/l) wird der Kolben