Draft oecd guideline for the testing

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DRAFT OECD GUIDELINE FOR THE TESTING OF CHEMICALS

www.oecd.org

1 DRAFT OECD GUIDELINE FOR THE TESTING OF CHEMICALS Test Guideline 453: Combined Chronic Toxicity\Carcinogenicity Studies INTRODUCTION 1. OECD Guidelines for the Testing of Chemicals are periodically reviewed in the light of

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OECD GUIDELINE FOR THE TESTING OF CHEMICALS

www.oecd.org

Paris 28 November 2008 Patric.amcoff@oecd.org OECD GUIDELINE FOR THE TESTING OF CHEMICALS DRAFT PROPOSAL FOR A NEW GUIDELINE: 436 Acute Inhalation Toxicity - Acute Toxic Class (ATC) Method

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Risk Assessment and Management of Genotoxic Impurities in ...

www.nihs.go.jp

Major Safety Issues of ICH Guideline for Genotoxic Impurities The focus of this guideline is on DNA reactive substances which can be detected by Ames assay. Application of Threshold of Toxicological Concern (TTC) to control genotoxic impurities.

Guidelines

Draft oecd guideline for the testing