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www.pi.amgen.comconjunction with chemotherapy and/or radiotherapy for signs and symptoms of MDS/AML. (5.8) Thrombocytopenia: Monitor platelet counts. (5.9) ... NEUPOGEN at least 24 hours after cytotoxic chemotherapy and at least 24 hours after bone marrow infusion. Monitor CBCs and platelet counts frequently following marrow transplantation.