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Fluorine NMR - Biophysical Society
www.biophysics.org1999). Fluorine-19 has a natural abundance of 100% and has a sensitivity to NMR detection that is 83% that of the sensitivity of . 1. H. Thus, introduction of fluorine produces a strong NMR signal that appears against a background devoid of signals from endogenous nuclei. Using a fluorine-labeling