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Protecting Groups Handout A - University of Houston

Protecting Groups Handout A - University of Houston

may.chem.uh.edu

Protecting Groups Hydroxyl Protection Methyl Ethers Formation: Stability: Cleavage: Adv./Disadv.:Methyl ethers, with the exception of aryl methyl ethers, are often difficult to remove. However, there are exceptions. AlBr 3,EtSH PhSe-Ph 2P-Me 3SiI Stable to Acid and Base CH 2N 2, SiO 2 or HBF 4 NaH, MeI, THF Methylthiomethyl Ethers (MTM ...

  Group, Protecting, Handouts, Protecting groups, Protecting groups handout a

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