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Search results with tag "Ibrutinib"
DRUG NAME: Ibrutinib - BC Cancer
www.bccancer.bc.catreated with ibrutinib, both with and without thrombocytopenia. Major hemorrhagic events, such as subdural hematoma, gastrointestinal bleeding, hematuria, and post-procedural bleeding are reported in 3% of patients. Bruton’s tyrosine kinase is expressed in platelets; however, the mechanism for bleeding events is not well understood.
For Health Professionals Who Care For Cancer Patients
www.bccancer.bc.ca– The BC Cancer Lymphoma Group is introducing ibrutinib as a new treatment for patients with relapsed after or refractory to standard treatments.
Ibrutinib inhibition of Bruton protein-tyrosine …
www.brimr.orgR. Roskoski Jr. / Pharmacological Research 113 (2016) 395–408 397 Fig. helices 1. Role of the Bruton protein-tyrosine kinase in B cell receptor signaling.