発表施設 題 氏名 発表 発表年 愛知県がんセン 2013 …

1 Functional variants at the 11q13 risk locus forbreast cancer regulate cyclin D1 expressionthrough long-range enhancersFrench JD, Ghoussaini M, Edwards SL, Meyer KB,Michailidou K, Ahmed S, Khan S, Maranian MJ,O'Reilly M, Hillman KM, Matsuo K, Ito H, Iwata H,Sueta A, Nevanlinna H, Brown MA, Chenevix-Trench G, Easton DF, Dunning AM et J Hum Genet, 92(4):489-503,20132013 Fine-Scale Mapping of the FGFR2 BreastCancer Risk Locus: Putative Functional VariantsDifferentially Bind FOXA1 and E2F1 Meyer KB, O'Reilly M, Michailidou K, Carlebur S,Edwards SL, French JD, Prathalingham R, Dennis J,Bolla MK, Wang Q, Matsuo K, Ito H, Iwata H,Yatabe Y, Orr N, Schoemaker MJ, Ponder BA,Dunning AM, Easton DF et J Hum Genet, 93(6):1046-60,20132013 High-Throughput LC-MS/MS BasedSimultaneous Determination of PolyaminesIncluding N-Acetylated Forms in Human Salivaand the Diagnostic Approach to Breast CancerTsutsui H, Mochizuki T, Inoue K, Toyama T,Yoshimoto N, Endo Y, Todoroki K, Min JZ,Toyo'oka TAnal Chem, 85(24):11835-42, 20132013 Sivelestat attenuates lung injury in surgery forcongenital heart disease with pulmonaryhypertensionNomura N, Asano M, Saito T, Nakayama T,Mishima AAnn Thorac Surg, 96(6):2184-91,20132013 Children undergoing liver transplantation fortreatment of inherited metabolic diseases areprone to higher oxidative stress, complementactivity and transforming growth factor- 1 Hussein MH, Hashimoto T, Suzuki T, Daoud GA,Goto T, Nakajima Y, Kato T, Hibi M, Tomishige H,Hara F, Kato S, Kakita H, Kamei M, Ito T, Kato I,Sugioka A, Togari HAnn Transplant, 18.

2 63-8, 20132013 Mitotic phosphorylation of MPP8 by cyclin-dependent kinases regulates chromatindissociationNishigaki M, Kawada Y, Misaki T, Murata K,Goshima T, Hirokawa T, Yamada C, Shimada M,Nakanishi MBiochem Biophys Res Commun,432(4):654-9, 20132013 Simultaneous knock-down of Bcl-xL and Mcl-1induces apoptosis through Bax activation inpancreatic cancer cellsTakahashi H, Chen MC, Pham H, Matsuo Y,Ishiguro H, Reber HA, Takeyama H, Hines OJ, EiblGBiochim Biophys Acta,1833(12):2980-7, 20132013 PD-L1 gene expression in Japanese lung cancerpatientsSasaki H, Suzuki A, Shitara M, Hikosaka Y,OkudaK, Moriyama S, Yano M, Fujii YBiomed Rep, 1(1):93-6, 20132013 Polymorphisms of NRF2 gene correlated withdecreased FEV1 in lung cancers of smokersSasaki H, Suzuki A, Shitara M, Hikosaka Y,OkudaK, Moriyama S, Yano M, Fujii YBiomed Rep, 1(3):484-6, 20132013 Randomized controlled trial of toremifene 120mg compared with exemestane 25 mg after priortreatment with a non-steroidal aromataseinhibitor in postmenopausal women withhormone receptor-positive metastatic breastcancerYamamoto Y, Ishikawa T, Hozumi Y, Ikeda M,Iwata H, Yamashita H, Toyama T, Chishima T, SajiS, Yamamoto-Ibusuki M, Iwase HBMC Cancer, 13(1):239, 20132013 A randomized, double-blind, controlled study ofexemestane versus anastrozole for the first-linetreatment of postmenopausal Japanese womenwith hormone-receptor-positive advanced breastcancerIwata H, Masuda N, Ohno S, Rai Y, Sato Y, OhsumiS, Hashigaki S, Nishizawa Y, Hiraoka M, MorimotoT, Sasano H, Saeki T, Noguchi SBreast Cancer Res Treat,139(2).

3 441-51, 20132013 Randomized trial of preoperative docetaxel withor without capecitabine after 4 cycles of 5-fluoracil-epirubicin-cyclophosphamide (FEC) inearly stage breast cancer: Exploratory analysesidentify Ki67 as a predictive biomarker forresponse to neoadjuvant chemotherapyOhno S, Chow LW, Sato N, Masuda N, Sasano H,Takahashi F, Bando H, Iwata H, Morimoto T,Kamigaki S, Nakayama T, Nakamura S, Kuroi K,Aogi K, Kashiwaba M, Yamashita H, Hisamatsu K,Ito Y, Yamamoto Y, Ueno T, Fakhrejahani E,Yoshida N, Toi MBreast Cancer Res Treat, 142(1):69-80, 20132013 A Novel adaptor protein Shf interacts with ALKreceptor and negativery regulates its downstreamsignals in neuroblastomaTakagi D, Tatsumi Y, Yokochi T, Takatori A, OhiraM, Kamijo T, Kondo S, Fujii Y, Nakagawara ACancer Sci, 104(5):563-72, 20132013 Analysis of Ki-67 expression with neoadjuvantanastrozole or tamoxifen in patients receivinggoserelin for premenopausal breast cancerIwata H, Masuda N, Sagara Y, Kinoshita T,Nakamura S, yanagita Y, Nishimura R, Iwase H,Kamigaki S, Takei H, Thsuda H, Hayashi N,Noguchi SCancer, 119(4):704-13, 20132013 Identification and association study with lungcancer for novel insertion polymorphisms ofhuman endogenous retrovirusKahyo T, Tao H, Shinmura K, Yamada H, Mori H,Funai K, Kurabe N, Suzuki M, Tanahashi M, NiwaH, Ogawa H, Tanioka F, Yin G, Morita M, MatsuoK, Kono S, Sugimura HCarcinogenesis, 34(11):2531-8, 20132013 Myoepithelial Carcinoma of the Breast Treatedwith Surgery and ChemotherapyEndo Y, Sugiura H, Yamashita H,TakahashiS,Yoshimoto N, Iwasa M, Asano, Toyama TCase Rep Oncol Med, 2013.

4 164761,20132013 Characteristics of Lung Cancers HarboringNRAS MutationsOhashi K, Sequist LV, Arcila ME, Lovly CM, ChenX, Rudin CM, Moran T, Camidge DR, Vnencak-Jones CL, Berry L, Pan Y, Sasaki H, Engelman JA,Garon EB, Dubinett SM, Franklin WA, Riely GJ,Sos ML, Kris MG, Dias-Santagata D, Ladanyi M,Bunn PA Jr, Pao WClin Cancer Res, 19(9):2584-91,20132013 Necrosis of large hepatocellular carcinomainduced by preoperative portal veinembolization: a case reportYasuda A, Kurokawa T, Nakao N, Fujisaki H, AndoK, Ito N, Ohashi N, Arikawa T, Tainaka T, NagataH, Suzumura K, Nonami TDig Dis Sci, 58(9):2729-32, 20132013 Establishment of a simple predictive scoringsystem for pancreatic fistula after laparoscopy-assisted gastrectomyMiyai H, Hara M, Hayakawa T, Takeyama HDig Endosc, 25(6):585-92, 20132013 MiR-1290 and its potential targets are associatedwith characteristics of estrogen receptor -positive breast cancerEndo Y, Toyama T, Takahashi S, Yoshimoto N,Iwasa M, Asano T, Fujii Y, Yamashita HEndocr Relat Cancer, 20(1):91-102,20132013 Alcohol and dietary folate intake and the risk ofbreast cancer: a case-control study in JapanIslam T, Ito H, Sueta A, Hosono S, Hirose K,Watanabe M, Iwata H, Tajima K, Tanaka H, MatsuoKEur J Cancer Prev, 22(4):358-66,20132013 NOTCH1 Expression Predicts Patient Prognosisin Esophageal Squamous Cell CancerOgawa R, Ishiguro H, Kimura M, Funahashi H,Wakasugi T, Ando T, Shiozaki M, Takeyama HEur Surg Res, 51(3-4).

5 101-7, 20132013 Genotyping analyses for polymorphisms ofANXA5 gene in patients with recurrentpregnancy lossHayashi Y, Sasaki H, Suzuki S, Nishiyama T, KitaoriT, Mizutani E, Suzumori N, Sugiura-Ogasawara MFertil Steril, 100(4):1018-24, 20132013 The herbal drug, polysaccharide K, has animmunological and synergistic anticancer effectwith cetuximab for gastrointestinal cancer invivoHara M, Nagasaki T, Takeyama HGJMR, 13(3):1-5, 20132013 Common genetic determinants of breast-cancerrisk in East Asian women: a collaborative studyof 23 637 breast cancer cases and 25 579controlsZheng W, Zhang B, Cai Q, Sung H, Michailidou K,Shi J, Choi JY, Long J, Dennis J, Humphreys MK,Matsuo K, Ito H, Iwata H, Tanaka H, Wen W, HallP, Shu XO, Easton DF, Kang D et Mol Genet, 22(12):2539-50,20132013 Multicenter phase II study of modifiedFOLFOX6 as neoadjuvant chemotherapy forpatients with unresectable liver-only metastasesfrom colorectal cancer in Japan: ROOF studyTakahashi T, Shibata Y, Tojima Y, Tsuboi K,Sakamoto E, Kunieda K, Matsuoka H, Suzumura K,Sato M, Naganuma T, Sakamoto J, Morita S, KondoKInt J Clin Oncol, 18(2):335-42, 20132013 A multicenter phase II study of TSU-68 a noveloral multiple tyrosine kinase inhibitor in patientswith metastatic breast cancer progressing despiteprior treatment with an anthracycline-containingregimen and taxaneSuzuki Y, Saeki T, Aogi K, Toi M, Fujii H, Inoue K,Watanabe T, Fujiwara Y, Ito Y, Takatsuka Y, IwataH, Arioka H, Tokuda YInt J Clin Oncol, 18(4).

6 590-7, 20132013 A phase II study of lapatinib for brain metastasesin patients with HER2-overexpressing breastcancer following trastuzumab based systemictherapy and cranial radiotherapy: subset analysisof Japanese patientsIwata H, Narabayashi M, Ito Y, Saji S, Fujiwara Y,Usami S, Katsura K, SasakiInt J Clin Oncol, 18(4):621-8, 20132013 Genotype analysis of the NRF2 gene mutation inlung cancerSasaki H, Suzuki A, Shitara M, Hikosaka Y, OkudaK, Moriyama S, Yano M, Fujii YInt J Mol Med, 31(5):1135-8, 20132013 Castleman's disease in the pelvicretroperitoneum: A case report and review of theJapanese literatureSato AInt J Surg Case Rep, 4(1):19-22,20132013 Adverse events of pulmonary vascular staplingin thoracic surgeryYano M, Takao M, Fujinaga T, Arimura T, Fukai I,Ota S, Saito Y, Okuda KInteract Cardiovasc Thorac Surg,17(2):280-4, 20132013 Surgical management of an aneurysm of the leftatrial appendage to prevent potential sequelaeNakai Y, Asano M, Nomura N, Mishima AInteract Cardiovasc Thorac Surg,17(3):586-7, 20132013 Anatomical repair of aortopulmonary windowwith anomalous origin of the right coronaryartery from the pulmonary arteryAsano M, Ukai T, Nomura N, Mishima AJ Card Surg, 28(6):767-9, 20132013 A case of fractured gide wire perforating thecoronary artery and ascending aorta duringpercutaneous coronary interventionIto S, Yoshida T, Suda HJ Cardiology Cases, 7(5):e137-41,20132013 A novel predictive strategy byimmunohistochemical analysis of four EGFR ligands in metastatic colorectal cancer treatedwith anti-EGFR antibodiesYoshida M, Shimura T, Sato M, Ebi M, Nakazawa T,Takeyama H, Joh TJ Cancer Res Clin Oncol,139(3).

7 367-78, 20132013 Biliary atresia type I cyst and choledochal cyst[corrected]: can we differentiate or not?Suzuki T, Hashimoto T, Hussein MH, Hara F, HibiM, Kato TJ Hepatobiliary Pancreat Sci,20(5):465-70, 20132013 Comparative analysis of MRSA strains isolatedfrom cases of mupirocin ointment treatment inwhich eradication was successful and in whicheradication failedOgura M, Yano H, Sato M, Nakamura A, WakimotoY, Ohkusu K, Ezaki TJ Infect Chemother, 19(2):196-201,20132013 Extracellular domain mutation of erbB2 status inJapanese lung cancer patientsSasaki H, Tatematsu T, Shitara M, OkudaK,Hikosaka Y, Moriyama S, Yano M, Fujii YJ Oncobiomarkers, 1(2):1-5, 20132013 Visceral pleural invasion classification in non-small-cell lung cancer in the 7th edition of thetumor, node, metastasis classification for lungcancer: validation analysis based on a large-scalenationwide databaseKawase A, Yoshida J, Miyaoka E, Asamura H, FujiiY, Nakanishi Y, Eguchi K, Mori M, Sawabata N,Okumura M, Yokoi K: Japanese Joint Committee ofLung Cancer RegistryJ Thorac Oncol, 8(5):606-611, 20132013 Results of T4 surgical cases in the JapaneseLung Cancer Registry Study: should mediastinalfat tissue invasion really be included in the T4category?

8 Watanabe S, Asamura H, Miyaoka E, Okumura M,Yoshino I, Fujii Y, Nakanishi Y, Eguchi K, Mori M,Sawabata N, Yokoi K: Japanese Joint Committee ofLung Cancer RegistryJ Thorac Oncol, 8(6):759-765, 20132013 Usefulness of immunohistochemistry for thedetection of the BRAF V600E mutation inJapanese lung adenocarcinomaSasaki H, Shimizu S, Tani Y, Shitara M, Okuda K,Hikosaka Y, Moriyama S, Yano M, Fujii YLung Cancer, 82(1):51-4, 20132013 Clinicopathological analysis of small-sizedthymoma with podoplanin and Ki67 expressionanalysisYokota K, Yano M, Moriyama S, Hikosaka Y,Okuda K, Shitara M, Okumura M, Yokoi K, Fujii YMol Clin Oncol, 1(1):88-92, 20132013 Weak brain damage under optimal-constantblood flow in ratAkihiro M, Akimasa I, Yuko S, Sachiyo M, NorikazuN, Tmohiko U, Miki A, Hideki H, Akira MNagoya Med J, 53(3):56-80, 20132013 Large-scale genotyping identifies 41 new lociassociated with breast cancer riskMichailidou K, Hall P, Gonzalez-Neira A,Ghoussaini M, Dennis J, Milne RL, Schmidt MK,Chang-Claude J, Bojesen SE, Bolla MK, Matsuo K,Ito H, Iwata H, Sueta A, Pharoah PD, Chenevix-Trench G, Dunning AM, Benitez J, Easton DF et Genet, 45(4):353-61, 20132013 Multiple independent variants at the TERT locusare associated with telomere length and risks ofbreast and ovarian cancerNat Genet, 45(4):371-84, 20132013 Oncogenic and drug sensitive NTRK1rearrangements in lung cancerVaishnavi A, Capelletti M, Le AT, Kako S, ButaneyM, Ercan D, Mahale S, Davies KD, Aisner DL,Pilling AB, Berge EM, Kim J, Sasaki H, Park SI,Kryukov G, Garraway LA, Hammerman PS, Haas J,Andrews SW, Lipson D, Stephens PJ, Miller VA,Varella-Garcia M, Janne PA, Doebele RCNat Med, 19(11).

9 1469-72, 20132013 Keap1 mutations in lung cancer patientsSasaki H, Suzuki A, Shitara M, Okuda K, HikosakaY, Moriyama S, Yano M, Fujii YOncol Lett, 6(3):719-21, 20132013 Girdin, a regulator of cell motility, is a potentialprognostic marker for esophageal squamous cellcarcinomaShibata T, Matsuo Y, Shamoto T, Hirokawa T,Tsuboi K, Takahashi H, Ishiguro H, Kimura M,Takeyama H, Inagaki HOncol Rep, 29(6):2127-32, 20132013 CD74-ROS1 fusion transcripts in resected non-small cell lung carcinomaMatsuura S, Shinmura K, Kamo T, Igarashi H,Maruyama K, Tajima M, Ogawa H, Tanahashi M,Niwa H, Funai K, Kohno T, Suda T, Sugimura HOncol Rep, 30(4):1675-80, 20132013 Final Results of a Safety and Efficacy Trial ofPreoperative Sequential ChemoradiationTherapy for the Nonsurgical Treatment of EarlyBreast Cancer