平成 23 年度報告 毒物劇物指定の ... - nihs.go.jp

1 23 CAS No. 137-26-8 24 3 1 LD50/LC50 >1000 mg/kg GHS 4 5 2000 mg/kg GHS 5 mg/L/4H GHS 4 GHS 1 EU CLP 1. LD50 LC50 2.

2 CAS No. LD50/LC50 30 Chemical Database (CD) MSDS [ ] International Chemical Safety Cards (ICSC) IPCS , [ 2 ] Fire Protection Guide to Hazardous Materials (NFPA, 13th ed.)

3 , 2002) NFPA CRC Handbook of Chemistry and Physics (CRC, 85th, 2004) CRC Merck Index (Merck, 14th ed., 2006) Merck and Company, Inc. ChemID US NLM TOXNET 1 [ ] GESTIS IFA [ ] Registry of Toxic Effects of Chemical Substances (RTECS) US NIOSH ( ) MDL Information Systems, Inc. [ , Inc ] Hazardous Substance Data Bank (HSDB) NLM TOXNET [ ] , Inc [RightAnswer ] International Uniform Chemical Information Database (IUCLID) ECB [ ] IUCLID Chemical Data Sheets Information System Patty s Toxicology (Patty, 5th edition, 2001)

4 Wiley-Interscience JECDB OECD GLP [ ] SAX s Dangerous Properties of Industrial Materials (SAX, 11th edition, 2004) Wiley-Interscience Environmental Health Criteria (EHC) IPCS 3[ ] Concise International Chemical Assessment Documents (CICAD) IPCS EHC [ ] EU Risk Assessment Report (EURAR) EU [ ] Screening Information Data Set (SIDS) OECD [ ] ATSDR Toxicological Profile (ATSDR) US ATSDR [ ] ACGIH Documentation of the threshold limit values for chemical substances (ACGIH , 7th edition, 2001) ACGIH MAK Collection for Occupational Health and Safety (MAK)

5 DFG [ ] TOXLINE US NLM [ ] PubMed US NLM [ ] Google Scholar (Google-S) Google [ ] Google Google [ ] ESIS (European chemical Substances Information System) ECB EU CLP[ ] [ ] Recommendation on the Transport of Dangerous Goods, Model Regulations (TDG 16th ed., 2009; 17th ed., 2011) [ ] [ ] 3. 4 SIDS EHC ACGIH MAK WHO IARC HCN EPA HPV EPA RED SDS CD ( 1) ATSDR ICSC ( 2) CICAD NFPA EURAR CRC ( 3) SIDS ( 11) Merck ( 4) EHC ( 12) ChemID ( 5) ACGIH ( 13) GESTIS ( 6) MAK ( 14) RTECS ( 7)

6 IARC ( 15) HSDB ( 8) HCN ( 16) IUCLID ( 9) JECDB SAX ( 10) EPA HPV ( 17) Patty EPA RED ( 18) SDS ( 19) TDG ( 20) ESIS ( 21) 2-8, 11, 13, 15 Thiuram, Thiram, Tetramethylthiuram disulfide, Bis (dimethylthiocarbamoyl) disulfide CAS 137-26-8 RTECS JO1400000 UN TDG 3077 ICSC 0757 EC (Annex I Index) 205-286-2 (006-005-00-4) C6H12N2S4 / (CH3)2N-CS-S-S-CS-N(CH3)2 1 g/cm3 (20 C) 129 C ( kPa) 156 C 89 C ( ) 10-5 mmHg (= Pa) (25 C) 1 18 mg/L / (Log P) 1 mL/m3 (1 ppm) = mg/m3 ( g/L)

7 [1 25 C] 1 5-19 ChemID 5 GESTIS 6 RTECS 7 HSDB 8 IUCLID 9 SAX 10 SIDS 11 EHC 12 ACGIH 13 MAK 14 IARC 15 HCN 16 EPA HPV 17 EPA RED 18 SDS 19 ChemID 5 6 LD50 (LC50) 560 mg/kg 1 1250 mg/kg 2 LDLo 5 g/kg (LD50: >5000 mg/kg) 3 LDLo 1 g/kg (LD50: >1000 mg/kg) 4 500 mg/m3/4H (= 51 ppm/4H)* 5 *.

8 Pa 25 C 106 x kPa /101 kPa = ppm 51 ppm g/L GESTIS 6 LD50 (LC50) 560 mg/kg 1 400 4000 mg/kg 6 / >1000 or >2000 mg/kg 6 mg/L/4H 5 >102 mg/m3/4H 6 300 1000 mg/m3/4H 6 >6225 mg/m3/4H 7 RTECS 7 LD50 (LC50)

9 560 mg/kg 1, 8 1800 mg/kg 8 1250 mg/kg 2 1350 mg/kg 8 4420 mg/m3/4H 8 500 mg/m3/4H 8 HSDB 8 LD50 (LC50)

10 560 mg/kg 9 1350 mg/kg 10 >2000 mg/kg 11 7 500 mg/m3/4H 9 IUCLID 9 LD50 (LC50) 1800 mg/kg # 12 560 mg/kg 1 2600 mg/kg # 12 1080 mg/kg # 13 1112 mg/kg ( ), 1278 mg/kg ( )