バイオテクノロジーが拓く 『ポスト第4次産業革命』

1 4 I 1 2 Synthetic Biology CRISPR/Cas9 DNA 2005 1/1 (1990 ) 1/1000 DNA 2000 1/1000 2013 CRISPR/Cas BuildTe s tLearnDesign AI.

2 IT DBTL IT/AI DNA 3 DNA 4 4 DNA/RNA IT AI Smart Cell 4 5 IoT IT AI IT AI OECD Bioeconomy 6 German Bioeconomy Council 2018 49 2018 2 Global BioecomonySummit 70 57 7 NEDO 2019 7 2019

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4 10 NEDO 30 31 3 CTMRI OTC SEM TEM/STEM 10,000100,0001,000,00010,000,000100,000, 0001,000,000,000020406080100 11 NEDOTSC foresight 2018 2 10 1 11632 SIEMENS 11483 6964 6805 6526 CARL ZEISS STIFTUNG 5827 GENERAL ELECTRIC 5378 SAMSUN ELECTRIC 5339 47910 462 01,0002,0003,000H26H27H28H29H30 ( )020406080H26H27H28H29H30 ( )

5 12 Nature Reviews Drug Discovery 19, 228 (2020) 10 2019 10 5 2 1 (10 )1 OECD Government budget allocations for R&D-Health- 05001,0001,5002,0002,5003,0003,5004,0004 ,500 200620102014201805,00010,00015,00020,000 25,00030,00035,00040,00045,000 2006201020142018 14 PY2005 -2007 - - Top 1 0 1 90.

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8 Nature Protocols 22 iPS 23 24 GinkgoBioworks DNA 24 NITE 25 CliniMACS Prodigy 2627 IT 28 AI NIH

9 MIT UCSD BIOCOM Illumina 2014 MedCity 2015 IT Bio Base Europe Pilot Plant Cell and Gene Therapy Catapult 2005 2009 2018 GMP GMP 661 184 3.

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