Agilent 1200 Series LC Systems and Modules

1 Agilent 1200 Series LC Systems and Modules 2. Agilent 1200 Series Pure Liquid Chromatography Agilent Technologies has taken its Agilent has been developing robust world leading LC system and made and reliable LC Systems for over it even more flexible, smarter and 30 years. The Agilent 1200 Series ultimately equipped for the future. represents the latest advance in this evolution of excellent integrated The new Agilent 1200 Series is finely solutions, designed to help you tuned to give you a winning combination achieve uncompromised data of speed, resolution and sensitivity, quality and higher productivity. while the modular design ensures that you get a configuration ideally Make a secure investment in the suited to meet your application future of your lab with the scalable requirements. and open architecture of the Agilent 1200 Series . All the performance. All the time. 3. Sensitivity and Performance Optimized to give you complete confidence in your results The seamless integration of each Mass selective detection HPLC-Chip/MS for reliable module gives you unparalled accuracy for more confidence high sensitivity nanospray and precision for both quantitative and qualitative analysis.

2 Highly sensitive By providing molecular weight The easy-to-use HPLC-Chip/MS. detectors deliver the lowest possible and structural information, which system significantly improves your detection limits for even the most complements the spectral information nanoflow separations by eliminating demanding applications. from a diode array detector, the Agilent all post-column dead volumes and 6000 Series LC/MS Systems are the is ideally suited for high sensitivity ideal solutions for scientists who need nanospray LC/MS with limited Spectral information from additional selectivity and sensitivity sample amounts. 190 to 950 nm for their chromatographic Systems . The dual-lamp design and the Limit of Detection: 10 fg or 32 attomoles Sulfadimenthoxine temperature control of the Agilent 1200 Series diode array detectors ensure outstanding sensitivity. Photodiode arrays with 1024. elements, programmable slit width (1, 2, 4, 8, 16 nm) and the selection of nine different flow cells enable Serum sample with HPLC-Chip/6320 Ion Trap LC/MS, optimization of resolution, linearity EIC of ( , , ), 1 L injection.

3 And sensitivity. Limit of detection of anthracene at different data rates with diode array detector. Revolutionary HPLC-Chip/MS integrates capillaries, nanocolumns and nanospray emitter on a single polymer chip. 4. Superior injection precision High resolution chromatography and lowest carryover reveals more The selection of different autosamplers Small particle size and long separation provides for precision levels of columns are key for higher efficiency < % RSD over an injection volume and resolution. The Agilent 1200. range from L to 2000 L. Series Rapid Resolution system fully The unique flow-through design, exploits the power of Agilent ZORBAX. combined with the external needle Rapid Resolution HT columns with wash and optional multiple wash m particles, providing a new solvents, virtually eliminates carryover, dimension of information for complex even for highly adsorptive compounds. samples. Injection volume [ L]. Typical repeatability data for injection volumes demonstrates the high precision of the standard autosampler.

4 High resolution chromatography of a ginseng root extract with the Agilent 1200 Series Rapid Resolution system and TOF detection, with the average peak width of minutes giving a peak capacity of 540. For more information visit: 5. Speed and Throughput Modular and scalable platform lets you decide just how fast you want to work By choosing a system from the fast Agilent 1200 Series Fast cycle time for quaternary/binary LC system through binary pump SL ultra-fast analysis to the ultra-fast rapid resolution system you can achieve new levels of Configurable delay volume down High performance autosamplers productivity, processing more samples to 120 L together with a flow enable fast injection cycles without in less time, while maintaining and range up to 5 mL/min provides sacrificing lowest carryover even improving data quality. universal applicability Valve solutions for alternating Short columns with sub-2 m Electronic damping control column regeneration particles offer a unique opportunity for lowest baseline noise Minimized run-to-run instrument to dramatically reduce analysis time Perfect choice for fast and and software initialization time by increasing the flow rate without precise gradients using LC/MS, losing separation performance.

5 As well as UV-only Systems In order to take full advantage of their power, you need a system that Fully exploits the speed and can do more than handle high back separation potential of ZORBAX. pressure. The answer is a fully Rapid Resolution HT columns integrated solution, optimized for system volumes, cycle times, detection rates and temperature control. mAU - Butyrophenone - Acetophenone 350. - Acetanilide - Propiophenone - Valerophenone 300. - Benzophenone - Heptanophenone - Hexanophenone - Octanophenone 250 PWHH = 197 milliseconds 200. Column: ZORBAX SB RRHT C18, mm x 50 mm, m Flow = mL/min 150. Gradient: water/acetonitrile 0 min 35 %. min 95 % 100. min 95 %. min 35 %. Temperature: 95 C 50. Pressure: 550 bar Detection: DAD SL, 80 Hz data rate 0. Ultra-fast separation of a phenone mix with the Agilent 1200 Series Rapid Resolution system . min 6 12 18 24 s 6. Complete ZORBAX Rapid High temperature enables Ultra-fast detectors with Resolution HT column portfolio higher speed uncompromised sensitivity The optimized particle size distribution The two independently controllable Programmable variable wavelength results in less back pressure which low volume heat exchangers detector VWD (55 Hz).

6 Makes these columns the number one allow ultra-fast, high temperature Multiple wavelength detector choice for all LC Systems . separation with unique post-column MWD (80 Hz). cooling for the lowest possible UV detection limits. Diode array detector for full spectral acquisition DAD (80 Hz). Five types of mass spectrometers, all with fast spectral acquisition that can keep up with the fastest chromatography Peltier cooling/heating ranging from 10 C below ambient up to 100 C. 80 Hz full spectral sampling rate provides resolution and peak capacity gains of 90 % relative to 10 Hz sampling rates. The ChemStation explorer enables fast data review. For more information visit: 7. Reliability and Lifetime Easy maintenance and intelligent system monitoring for increased uptime With an installed base of more than Robust components Agilent system intelligence 60,000 LC Systems , Agilent LC. technology is renowned for its Long-life pistons and seals, Early Maintenance Feedback (EMF).

7 Reliability under all operating together with active seal wash, tracks system usage (such as lamp conditions. The Agilent 1200 Series reduce the frequency of preventive burn time, solvent usage) and alerts represents the next generation of LC, maintenance you for timely replacement of parts designed for even greater robustness Deuterium and xenon lamps with Column identification module and reliability together with enhanced a lifetime of over 2000 hours records column parameters (such performance. as number of injections, particle Patented orthogonal spray design Agilent pioneered technologies to size and maximum pressure) and substantially reduces ion source monitor and track important system provides a unique column signature contamination and the need for parameters with the goal of ensuring cleaning Patented RFID tracking technology that you achieve greater productivity in the DAD SL saves all relevant and keep operating costs low.

8 Easy maintenance meta data from the flow cells Demonstration videos on a and UV lamp multimedia CD-ROM guide you Control Area Network (CAN). through maintenance procedures provides inter-modular, real-time Easily interchangeable ion sources communication for reliable operation, regardless of PC. E-Pac design significantly reduces failures or network interruptions assembly and disassembly time Software independent LC diagnostic tool assists users and the support experts interpreting the instrument status Agilent system intelligence provides a new generation of services with on-demand remote connectivity for a new level of productivity Self-aligning, front access to replacement parts, such as lamp and flow cells. A unique embedded data recovery card for DAD SL offers you data-never-lost insurance . 8. Customer support and services Agilent provides customer-focused products and services for all stages in an instrument's life cycle, from installation and upgrade to operation and repair.

9 The Agilent global network of support services offers a broad range of options for customized or contract services, enabling you to choose the package which best suits your laboratory needs and budget requirements. Agilent intelligent services Using the remote capabilities of your instrument, the latest generation of Agilent services offers real-time insight into instrument utilization and performance. Backed by highly skilled Agilent service engineers and application scientists, these intelligent services provide a whole new level of performance. Agilent LC diagnostics instrument status report includes all important information, such as system At the push of a button, Agilent LC diagnostics generates configuration, error log book, complete instrument status reports in pdf format. EMF and guidance report Maximized lab productivity secure and streamlined communication Intelligent Services Dedicated between your lab and the Agilent Gateway(s) Intelligent Services support organization Collects data from Enterprise Server Optimized return on instrument your instruments capital proactively monitor instrument performance and Intelligent Services utilization Gateway Controller Gives you complete control of data flow and access privileges Agilent Your Laboratory Network Support Infrastructure For more information visit: 9.

10 Open and Organized Scalable and open software architecture with Agilent OL operating system In parallel to the development of ChemStation for research and EZChrom Elite for maximum enhanced analytical hardware, method development tasks flexibility and compliance Agilent develops software solutions designed to meet your specific needs. Agilent ChemStation enables you Agilent EZChrom Elite workstation The Agilent range extends from to acquire, review and organize large is an easy to use software solution single workstations through to client- amounts of data, giving you instant for labs with instruments from server solutions and an innovative access to online instrument multiple vendors. It also provides informatics framework to unite your modifications and results. The built-in high automation capability with enterprise, ensuring that you can macro language makes it easy to advanced smart sequencing and expand your operations easily customize and the software supports reporting capabilities with automated and effectively.