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Antidepressants for the Geriatric Population

Tricyclic Antidepressants . Imipramine (Tofranil) 50 to 150 . 25-50 mg at bedtime . Increase 10 to 25 mg weekly to 150 mg . Effective for neuropathic pain. Serum drug levels can guide dosing . Anticholinergic, can exacerbate cardiac conduction problems. Use with caution if history or urinary retention or glaucoma.

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