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APOPTOSIS AND NECROSIS

in alcoholic liver disease, see the article by McClain et al., pp. 317–320.) Two cytokines that can induce apoptosis are TNF-αand TGF-β1.3 In the liver, TNF-αis produced and secreted by a certain type of immune cell called Kupffer cells. Several studies have found that TNF-αlevels were elevated in patients

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  Necrosis, Mcclain

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