付表ⅣB 完成品である薬品の製造に用いられるその …

1 (Sub-heading) -4-(p- ) trans-4-(p-chlorophenyl) ( -D- ) (alpha-D-glucopyranosylthio) 1- -2-( ) 1-chloro-2-(chlorodiphenylmethyl) ,4- -2- alpha, 2-[(1S,2R)-6- -2- -1- -1,2,3,4- -2- ] p- 2-[(1S,2R)-6-fluoro-2-hydroxy-1-isopropy l-1,2,3,4-tetrahydro-2-naphthyl]ethyl 2,3,5- 2,3, 4-[2-( ) ] 4-[2-(cyclopropylmethoxy)ethyl] 11- - -4- -3,20- 11-alpha-hydroxypregn-4-ene-3, 5,6- -1- 5, 9- ,11- - -17,21- -16- - -1,4- -3,20- 9-beta,11-beta-epoxy-17,21-dihydroxy-16- alpha-methylpregna-1,4-diene-3, 21- -9- ,11- - -17- -16- - -1,4- -3,20- 21-chloro-9-beta,11-beta-epoxy-17-hydrox y-16-alpha-methylpregna-1,4-diene-3, 20- -5,16- -3- - 20-oxopregna-5,16-dien-3-beta-yl pentyl (E)- -4- -1,8- (E)

2 -oct-4-ene-1,8-dioic 3- -1,1,1- triethyl 3-bromopropane-1,1, -5- indan-5-yl hydrogen -L- dibenzoyl-L-tartaric {(1R,3R,5S)-3,5- -2-[(E)-(3S)-3- -1- ] } {(1R,3R,5S)-3,5-dihydroxy-2-[(E)-(3S)-3- hydroxyoct-1-enyl]cyclopentyl}acetic DL- ethyl 3- -o- 3-chloroformyl-o-tolyl (R)-2-(3- ) (R)-2-(3-benzoylphenyl)propionic (RS)-2-(3- ) (RS)-2-(3-benzoylphenyl)propionic 3-[(3aS,4S,7aS)-7a- -1,5- -1H- -4- ] 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxooctah ydro-1H-inden-4-yl]propionic 7- -2- ethyl 2-(3- )-3- methyl 2-(3-nitrobenzylidene) (RS)-2-(6- -2- ) (RS)-2-(6-methoxy-2-naphthyl)propionic 7-[(3RS)-3- -5- -1- ] methyl 7-[(3RS)-3-hydroxy-5-oxocyclopent-1-enyl ] (2R,3S)-2,3- -3-(4- ) methyl (2R,3S)-2,3-epoxy-3-(4-methoxyphenyl) (2- )

3 (2-chloroethyl)diisopropylamine N,N'- ( )N,N'-dibenzylethylenediammonium di(acetate) (1S,2R)-1- -2- (1S,2R) 4'-[2-( ) ]-2- 4'-[2-(dimethylamino)ethoxy] (S)-5- -2-( )-1,6- -4- -3- (S)-5-amino-2-(dibenzylamino)-1, 2- -5- -2'- 2-amino-5-chloro-2' (-)- -( ) (-)-alpha-(chloroformyl)benzylammonium 2-(N- ) 3- -2- 2-(N-methylbenzylamino)ethyl 3-(4- )-L- 3-(4-nitrophenyl)-L-alanine IVB 1 8 (Sub-heading) 5- -2,4,6- 5-amino-2,4,6-triiodoisophthaloyl L- --p- (1:1)benzyl L-alaninate--p-toluenesulfonic acid (1:1) (4- )-L- methyl (4-nitrophenyl) (2S)-2- -3- -N- -- (1:1)(2S)-2-amino-3-hydroxy-N-pentylprop ionamide--oxalic acid (1.)

4 1) L- -L- -L- -L- -L- -L- -L- -L- -L- -L- -L- -L- -L- -L- -L- -L- -L- -L- -L- -L- -L- (2S,3S)-3-( )-2- -4- (2S,3S)-3-(tert-butoxycarbonylamino)-2-h ydroxy-4-phenylbutyric 2-[ -(4- ) ]-4- -3- 2-[alpha-(4-fluorobenzoyl)benzyl] 2- -N-[2-(2- )-4- ] 2-chloro-N-[2-(2-chlorobenzoyl)-4-nitrop henyl] 3'- -4'- 3'-acetyl-4' N-( )-L- N-(benzyloxycarbonyl) (2R,3S)-3- -2- -3- methyl (2R,3S) [(1S,2S)-1- -2,3- ] tert-butyl [(1S,2S)-1-benzyl-2,3-dihydroxypropyl] [(1S,3S,4S)-4- -1- -3- -5- ] tert-butyl [(1S,3S,4S)-4-amino-1-benzyl-3-hydroxy-5 -phenylpentyl] {(S)- -[(S)- ] } tert-butyl {(S)-alpha-[(S)-oxiranyl]phenethyl} (S)-3-(4- )-2- ethyl (S)-3-(4-aminophenyl)-2-phthalimidopropi onate (S)-3-{4-[ (2- )]}

5 ] }-2- ethyl (S)-3-{4-[bis(2-chloroethyl)amino]phenyl }-2-phthalimidopropionate -N- -3- -1,2- meso-N-benzyl-3-nitrocyclopropane-1, (Z)-(2- ) p- (Z)-(2-cyanovinyl)trimethylammonium 4-(2,2,3,3- ) 4-(2,2,3,3-tetrafluoropropoxy) (1- ) ethyl (1-cyanocyclohexyl) (Z)-[ (2,3- ) ] (Z)-[cyano(2,3-dichlorophenyl)methylene] N-( )-S- -L- N-(benzyloxycarbonyl) N-{2-[( ) ]-3-(o- )-1- }-L- ethyl N-{2-[(acetylthio)methyl]-3-(o-tolyl)-1- oxopropyl} (1R,2S)-3- -2- -1-( ) benzyl (1R,2S)-3-chloro-2-hydroxy-1-(phenylthio methyl) (Z)-2- -2-(2- ) ammonium (Z)-2-methoxyimino-2-(2-furyl) (3aR,4bS,4R,4aS,5aS)-4-(5,5- -1,3- -2- ) [3,4] [1,2-b] -2(3H)- (3aR,4bS,4R,4aS,5aS)-4-(5,5-dimethyl-1,3 -dioxolan-2yl)hexahydrocyclopropa[3,4]cy clopenta[1,2-b]furan-2(3H) (3aR,4R,5R,6aS)

6 -4- -2- -2H- [b] -5- (3aR,4R,5R,6aS)-4-formyl-2-oxohexahydro- 2H-cyclopenta[b]furan-5-yl 3- -4- -21,17- - 3-oxopregn-4-ene-21, 4'- 4' - - - 10- III10-deacetylbaccatin III2 8 (Sub-heading) 2- -2- - -D- 3,4-( ) 3,4-(methylenedioxy) 3- - -5- - -12- -6- -2,2- -1,3- -5- trans-6-amino-2,2-dimethyl-1, [(4R,6R)-6-( )-2,2- -1,3- -4- ] tert-butyl [(4R,6R)-6-(cyanomethyl)-2,2-dimethyl-1, 3-dioxolan-4-yl] [(2,3- -1,5- -3- -2- -1H- -4- ) ] magnesium bis[(2,3-dihydro-1,5-dimethyl-3-oxo-2-ph enyl-1H-pyrazol-4-yl)methylamino] 3- -4- 3-aminopyrazole-4-carboxamide 5- -1- -4- (RS)-2-[(1- -4- ) ]-5,6- -1- (RS)-2-[(1-benzyl-4-piperidyl)methyl]-5, 1-(2- )-3-( -1- )-1-(p- ) -1- 1-(2-pyridyl)-3-(pyrrolidin-1-yl)

7 -1-(p-tolyl) 1-[2-(4- ) ] 1-[2-(4-carboxyphenoxy)ethyl] 1-[2-(4- ) ]-4- 1-[2-(4-methoxyphenyl)ethyl] 1- -1,2,5,6- -3- (E)-o- 1-methyl-1,2,5,6-tetrahydropyridine-3-ca rbaldehyde (E)-O-methyloxime 2,2- -4- 2, 2-[(1- -4- ) ]-5,6- -1- 2-[(1-benzyl-4-piperidyl)methylene]-5, 2- -3- 3-[2-(3- ) ]-2- 1- -4- 3-[2-(3-chlorophenyl)ethyl]-2-pyridyl 1-methyl-4-piperidyl ketone 3-[2-(3- ) ] -2- 3-[2-(3-chlorophenyl)ethyl] 4- -4- p- 4-carboxy-4-phenylpiperidinium 5-(1- -4- )-5H- [a,d] -5- 5-(1-methyl-4-piperidyl)-5H-dibenzo[a,d] cyclohepten-5-ol 6- -2- p- 6-bromo-2-pyridyl p-tolyl 8- -6,11- -11-(1- -4- )-5H- [5,6] [1,2-b] 8-chloro-6,11-dihydro-11-(1-methyl-4-pip eridylidene)-5H-benzo[5,6]cyclohepta[1,2 -b] N-( )

8 -3- -2- N-(tert-butyl) -3- (2- ) benzyl(2-pyridyl) (3S,4aS,8aS)-N-( )-2-[(2S,3S)-2- -3-(3- -2- )-4-( ) ] -3- (3S,4aS,8aS)-N-(tert-butyl)-2-[(2S,3S)-2 -hydroxy-3-(3-hydroxy-2-methylbenzamido) -4-(phenylthio) butyl] (3S,4aS,8aS)-N-( )-2-[(2S,3S)-2- -3-(3- -2- )-4-( ) ] -3- -- (1:1)(3S,4aS,8aS)-N-(tert-butyl)-2-[(2S, 3S)-2-hydroxy-3-(3-hydroxy-2-methylbenza mido)-4-(phenylthio)butyl]perhydroisoqui noline-3-carboxamide--methanesulfonic acid (1:1) (9S,13S,14S)-3- (9S,13S,14S)-3-methoxymorphinan 1- -6,7- -8- -4- -1,4- -3- 1-cyclopropyl-6,7-difluoro-8-methoxy-4-o xo-1,4-dihydroquinoline-3-carboxylic 3-[(E)-2-(7- -2- ) ] 3-[(E)-2-(7-chloro-2-quinolyl)vinyl]b