cobas c 311 analyzer - Roche

1 cobas c 311 analyzerRoche Diagnostics introduces the cobas brand as the umbrellafor products used to complete or expand the screening, diagnosticand monitoring applications of the professional brand includes: serum work area with clinical chemistry and immunochemistry data management and preanalytical solutions products for coagulation analysis and urinalysis instruments for rapid blood and cardiovascular testing Polymerase Chain Reaction-based applications for virology and women s health testingcobas brandToday s laboratories are challenged with delivering high standards of laboratory services with fewer resources. They face constant pressure to lower operating costs while aspiring to grow their business in new areas. Their concern for patient care is paramount, and they demand only the best in diagnostic testing and as every patient requires individualized care, every laboratory is unique.

2 Striking the balance between high standards and efficient operation requires tailor-made solutions. With cobas modular platform, Roche has developed a platform concept that delivers individualized solutions based on a common architecture for various workloads and testing 4000 is the second member of the new cobas modular platform. It offers small workload laboratories a complete solution for clinical chemistry and immuno- chemistry modular platformFlexibility you can build onCommon universal reagent carriers Simplifies logistics Efficient use of reagentsCommon applications and analytical technologies Comparable patient results Combines routine and innovative testingCommon operator interface Requires less training Promotes staff flexibilityThe cobas modular platform is designed to reduce the complex-ity of laboratory operation and provides efficient and compatible solutions for network Operator interface5 Analytical modules180 Different assays availableThe clinical chemistry analyzer cobas c 311 5th generation of routine and dedicated chemistry

3 ExperiencesHitachi 700 seriesHitachi 900 series2nd generationCOBAS INTEGRA3rd generationMODULAR ANALYTICS4th generationcobas 4000 analyzer series5th generation1st generationThe clinical chemistry analyzer cobas c 311 5th generation of routine and dedicated chemistry experiencesReagentsOne grip handling of reagents The unique concept of the cobas c packs allows for convenient reagent handling. All reagents are ready to use. On board stability of reagents is up to 3 months and guarantees efficient usage even for esoteric assays. Over 90% of all reagents require lot calibration. Over 70% of all reagents require a sample volume of less than l. cobas c pack multi enables development channels for user defined reagent c 311 analyzerFeaturesStand alone analyzer for Clinical system for consolidating routine and special chemistry work loads.

4 On-board capacity of 45 tests and throughput of up to 480 tests per analysis of serum, plasma, urine, cerebrospi-nal fluid (CSF), hemolysate and whole workload consolidation cobas c 311, with up to 45 tests on board, offers consolidated testing from a menu of more than 100 applications. Enhanced lab efficiencyEliminating reagent preparation and manual sample handling contribute to time savings, faster result availability and turna-round time. Reduced costsLong on-board reagent stability and long calibration intervals mean fewer calibrations and less waste. PZTR eflectorUltra-sonic mixingIncreased security of resultsSample integrity is checked via the analyzers high sensitivity pressure sensors and clot detection systems minimizing the likelihood of volume management optimized for paediatrics 75% of all cobas c 311 analyzer applications need less than 5 l sample material.

5 For all short samples/aliquots the combination of micro sample cups, active level detection and volume optimized applications supports the use of paediatric sample material. Whole blood HbA1c capabilities cobas c 311 enables HbA1c in random access without manual sample preparationUltra sonic mixing setting the future standard for mixing today! The new ultra sonic mixing technology prevents potential carry-over by stirrers, reduces service and maintenance c 311 analyzerSpecificationsSystemFully automated, random access analyzer for Clinical chemistry and Homogeneous Immunology (HIA).Sample throughputUp to 300 samples/hr (theoretical max)Test throughput (Theoretical max) 300 tests/hr for photometry tests only480 tests/hr for only ISE testsNumber of channels (Reagent slots) 42 cassette slots3 channels on ISE moduleProgrammable parametersmax.

6 117 photometric3 ISE tests, 8 formulas, 3 serum indicesSample typesSerum, Plasma, Urine, CSF, Whole Blood (HbA1c only)Sample input (Sample disk) Load capacity: total 110 positions 55 positions on the outer ring 55 positions on the inner ring (outer & inner ring barcode read, sample detection available)STAT: real STAT interrupt is availablecontinuous operation: additional sample loading during operationSample container typesPrimary tubes 5 10 ml, 16 x 100, 16 x 75, 13 x100, 13 x 75mmSample cup 2,5 mlMicro cup 1,5 mlCups on tube Cup on top of a 16 x 75/100 mm tube Cup on top of one non standard tube false bottom tubeSample 35 l in l stepsSample dilution3 121 times, diluent 100 lSample clot detectionAvailableMinimum sample volumePrimary tubes : 700 lSample cup: 100 lMicro cup.

7 50 lSample barcode typesCode 128 Codabar (NW 7)Interleaved 2 of 5 Code 39 System interfacesRS 232 serial interface, bi-directionalInterface to cobas link (TeleService and automatic download of applications and package inserts) cobas c 311 analyzerSpecificationsSample data routine / STAT samplesTest methodsFor photometric modules: 1 point, 1 point + prozone check, 2 point, 2 point kinetic,2 point +prozone check, 3 point, 1 point + kinetics, Rate A, Rate A + serum index,Rate A with blank, Rate BCalibrator/QC InputOn the sample disk, bar codedCalibration methodsStart-up, Re-calibrationfor photometric assays: Linear, non-linear multi-points, 2 point calibration, K-factorup to 100 calibrators pre-programmableStorage of up to 180 curvesPreventive calibration of the stand-by cassettesTwo k-factor can be defined for different sample typesQC methodsReal-time QC, individual QC, cumulative QCup to 100 different controls pre-programmablepreventive QC after calibration of stand-by cassettesAuto QC (without operator intervention.)

8 Time- or event-triggered)Rerun/reflex functionAutomatic rerun and manual rerunAutomatic reflex is supported by the system if reflex request is provided by a PSM or LISE lectrical requirementsPower requirements: 230/400 Volts AC 3/N/PE 110 Volts AC kVAFrequency: 50 Hz or 60 Hz +/- 0,5 %Water/waste requirementsWater: Bacteria free, deionised water supply: resistance of 1,0 S/cm consumption: Up to 12 l/hr during operationWater pressure: 0,5 3,5 kg / cm3, (49 343 Kpa)Water temperature: 15 to 30 CBiohazards waste: Separate container located in the systemL. concentrated Central drain port, diameter: 50 mm,wall drain <?> waste: 100 mm above the floorRegulatory requirementsGS, CE, UL, C-ULOperating conditionsAmbient temperature: 15 to 32 CAmbient humidity: 45 to 85 % (RH, without condensation)Heat Output: 2 kcal/hNoise Output: < 65 dBPhysical dimensionsWidth: 1338 mmDepth: 855 mmHeight.

9 1262 mmWeight270 kgcobas c 311 analyzerAssay menuSubstratesAlbuminAmmoniaBicarbonateB ilirubin-directBilirubin-totalCalciumCho lesterolHDL-CholesterolLDL-CholesterolCr eatinine Jaff FructosamineGlucoseIronLactateMagnesiumP hosphorusTotal ProteinTotal Protein U / CSFT riglyceridesTriglycerides GBUIBCUrea / BunUric AcidEnzymesACPALPALT/GPTA mylase / GOTC holinesteraseCKCK-MBGGTGLDHHBDHLDHL ipaseDrugs of AbuseAmphetaminesBarbituratesBenzodiazep inesCannabinoidsCocain MetaboliteEthanolMethadoneEDDP*Methaqual oneOpiatesOxycodone*PhencyclidinePropoxy pheneLSDO thersAnti Trombin (AT III)T4T-UptakeTPLA**ElectrolytesChloride PotassiumSodium* Assay is under development** Not available in all countriesTDMA cetaminophenAmikacinCarbamazepineCyclosp orine*DigitoxinDigoxinGentamicinLidocain eLithiumMPANAPAP henobarbitalPhenytoinProcainamideQuinidi neSalicylateTheophyllineTobramycinValpro ic AcidVancomycinProteins 1-Acid GlycoproteinHaptoglobin 1-AntitrypsinHomocystein 1-MicroglobulineHbA1c (whole blood) 1-MicroglobulineIgAAlbumin (immuno.)

10 IgGAPO A1 IgMAPO BIMAASLOK appa Light ChainsC3cLambda Light ChainsC4 Lipoprotein (a)CeruloplasminMyoglobinCRPP realbuminCRP High SensitivityRFCystatin CSoluble Transferrin ReceptorD-DimerTransferrinFerritinCOBAS, cobas C and LIFE NEEDS ANSWERSBSF USBEFNBSLT PG 3 PDIF 3 PDIFR oche Diagnostics GmbHD-68298 8805599911001 0509 - CD