Transcription of ｢わが国の健常人におけるESBL産生菌の分離状況と特徴｣
1 2016 12 28 esbl - - - - ( extended - spectrum -lactamase, esbl ) - Ambler A D Bush-Jacoby-Medeiron 2 - esbl 2 TEM-1 SHV-1 TEM-1 - CTX-M CTX-M 100 - esbl AmpC 2000 esbl
2 esbl 2015 JANIS esbl 25% esbl CTX-M-15 B2 O25b:H4 Multilocussequencetyping(MLST) serotype(ST)131 FimH H30 CTX-M CTX-M-15 IncF IncF blaTEM-1 blaOXA-1 aac(6 )-Ib-cr CTX-M-15 - esbl esbl 2 3 esbl esbl 2 esbl esbl
3 - CTX-M- esbl O25b:H4-ST131 FimH H30 H30 ST 3 esbl esbl F esbl esbl esbl esbl 4 esbl
4 esbl esbl esbl (2001 ) 2002 2010 WHO esbl 3% 40-60% esbl esbl 2010 esbl 2010 1 2011 12 2 2,563 ( 1,050 / 1,513 ) 4,314 2,230 70 ( ) 333 52 ( ) esbl 145 3 1 ( ) ( )
5 esbl esbl 145 138 CTX-M CTX-M-14( ) CTX-M-15( ) CTX-M-27( ) CTX-M-2( ) O O25b(27 ) O1(11 ) O153(8 ) CTX-M O25 O1 O O25 O1 esbl esbl CTX-M-27 O25 MIC CTX-M-15 MIC CTX-M-15 O25b:H4-ST131-H30 CTX-M-27 O25b.
6 H4-ST131 52 13 esbl 3 2 2500 esbl O25b:H4-ST131 O1:H6-ST648 esbl CTX-M 9 CTX-M-14 -27 85% IncF IncFIB esbl IncF 3 85% esbl esbl 2 esbl esbl esbl ICU esbl
