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Fatty Acid Biosynthesis

stimulates FA biosynthesis. • The mechanism of hormonal regulation is covalent phosphorylation of acetylCoA carboxylase, the rate-limiting step of FA biosynthesis. • Acetyl CoA carboxylase is inhibited by phosphorylation. Phosphorylated acetylCoA carboxylase can regain partial activity by allosterically binding citrate.

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