Transcription of 醫學新知與專欄 第二型糖尿病新藥介紹: GLP-1 (類升糖素胜 肽 …
1 : GLP-1 ( -1 glucagon -like peptide-1 .. : GLP-1 ( . -1 glucagon -like peptide-1 .. peptidase 4 DPP-4) .. (incretin) . (glucagon-like peptide 1 T2DM . GLP-1 ) (distal (incretin action) . ileum) (colon) DPP-4 . (incretinmimetics) . GLP-1 DPP-4 (DPP-4. inhibitor) . ( cells) (glucagon-like peptide 1. (insulin) agonists, GLP-1 agonists) . ( cells) .. (glucagon) . GLP-1 T2DM .. GLP-1 .. (gastric emptying) .. (satiety sensation) .. GLP-1 . -4 (dipeptidyl -1 . 252. JOURNAL OF KAOHSIUNG MEDICAL ASSOCIATION 2015. vol. 23, glucagon-like peptide-1 L . agonists, GLP-1 agonists GLP-1 . -4 dipeptidyl . peptidase-4 inhibitors, DDP-4 . inhibitors .. GLP-1 T2DM . GLP-1 .. 1 GLP-1 . 253. : GLP-1 ( -1 glucagon -like peptide-1 .. Exendin-4 Gila GLP-1 . monster . GLP-1 GLP-1 . DDP-4 Exenatide . exendin-4 . metformin . glitazone . GLP-1 . Exenatide . GLP-1 Byetta 5 g .. 6 . 60 . 10 . Bydureon . 2 mg .. Exenatide . T2DM HbA1C . GLP-1 6 . T2DM . GLP-1 exenatide .. GLP-1 T2DM . exenatide .. Liraglutide . exenatide GLP-1 .)))
2 Byetta , Bydureon , . liraglutide Victoza , . GLP-1 . 254. JOURNAL OF KAOHSIUNG MEDICAL ASSOCIATION 2015. vol. 23, GLP-1 . Liraglutide T2DM . HbA1C exenatide T2DM .. exenatide .. exenatide 1. -incretin . DDP-4 .. 137-140.( . GLP-1 2005 ). DPP-4 2. Henriksen JH, de Muckadell OB. 2006 S e c r e t i n , i t s d i s c o v e r y, a n d t h e introduction of the hormone concept. Scand J Clin Lab Invest 2000; 60: 463- HbaA1C GLP-1 71. 3. AK. Mitra Assemi Betsy AC. Diabetes HbaA1C Mellitus. In: Koda-Kimble Mary Anne HbaA1C GLP-1 et al. Applied Therapeutics: The Clinical Use Of Drugs, 9th ed. 2009, Chap. 50. Mellitus. In: Pharmacotherapy: A Pathophysiologic Approach, 8th ed. 2009, Chap. 83. T2DM J Schen. A Review of gliptins in GLP-1 2011. Pharmacother. 2012, 13(1):81-99. 255.
