Example: bankruptcy
Guidelines for Endpoints in Animal Study Proposals
by the ACUC.1 A humane endpoint is the earliest scientifically justified point at which pain or distress in an experimental animal can be prevented, terminated, or relieved, while meeting the scientific aims and objectives of the study. Such endpoints are preferable to death or moribundity since they minimize pain
Tags:
Information
Domain:
Source:
Link to this page:
Documents from same domain
Guidelines for Blood Collection in Mice and Rats
oacu.oir.nih.govIn mice, general anesthesia is recommended if compatible with experimental design. If retro- orbital bleeding is conducted without general anesthesia, a topical ophthalmic anesthetic e.g. proparacaine or tetracaine drops, must be applied prior to the procedure.
Guidelines for Standards of Care in Animal Shelters
oacu.oir.nih.govThe Association of Shelter Veterinarians (ASV) is an international organization whose mission is to improve the health and well-being of animals in shelters through the advancement of shelter medicine. This document is the result of work that the ASV began in 2008 to address the lack of guidelines or standards of care for animals in shelters.
GUIDELINES FOR THE EUTHANASIA OF MOUSE AND RAT …
oacu.oir.nih.govpregnant dam should ensure rapid cerebral anoxia to the fetus with minimal disturbance to the uterine milieu minimizing fetal arousal.7 Methods for euthanasia of the dam should follow recommendations of the ARAC Guidelines for Euthanasia of Rodents Using Carbon Dioxide and the AVMA Guideline for the Euthanasia of Animals.
Administration Routes - OACU
oacu.oir.nih.govMice & Rats -Intramuscular Injection (IM) IM injections are administered in the thigh muscles of the hind limb. Caution must be used to avoid injury to the sciatic nerve, which is located in close proximity to the femur. 1. Restrain the animal by grasping the skin along its back with your left hand (if right-handed). 2.
INTRAVENOUS INJECTION (IV) - National Institutes of Health
oacu.oir.nih.govINTRAVENOUS INJECTION (IV) IV injections are administered to rabbits in the . marginal ear vein. The picture below illustrates the location of the vein. 1. Place animal in appropriate restraint device. 2. Shave the hair over the marginal ear vein. 3. Clean injection site with alcohol. 4. Insert a small bore (22 – 30 gauge) needle with a ...
Injection Routes, Maximum Needle Sizes & Volumes
oacu.oir.nih.govInjection Subcutaneous Injection Mouse. Skin Volume: <0.05ml Needle: <25 Gauge Rear Leg/Thigh Volume: <0.05ml Needle: <23 Gauge Abdomen - Lower Quadrant Volume: <2-3ml Needle: <21 Gauge Lateral Tail Vein Volume: <0.2ml …
Related documents
UKRI TRAINING GRANT GUIDANCE To be read with: UKRI ...
www.ukri.organaesthesia, analgesia and humane endpoints should be used to minimise any pain and suffering. TGC 3.3 Health and Safety . Staff and Research Participants . Appropriate care must be taken where Students and Supervisors are working on and off -site.
Research Instructions for NIH and Other PHS Agencies
grants.nih.govforms version f series released: october 16, 2020 research instructions for nih and other phs agencies sf424 (r&r) application packages