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High-dose Methotrexate (3.5g/m2) for CNS …
The dose of folinic acid should also be increased by if serum creatinine increases > 50% from baseline.
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LCA Haemato-Oncology Clinical Guidelines
www.londoncanceralliance.nhs.ukLCA Haemato-Oncology Clinical Guidelines Acute Leukaemia s and Myeloid Neoplasms. Part 1: Acute Lymphoblastic Leukaemia . April 2015
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