포사맥스플러스 포사맥스플러스디 - 한국MSD

1 399 1/11 TM TM < > 1 ( 325 mg) : (EP) ( 70 mg) ---------------------------------------- ---------- mg : (EP) ( D3 2800 ) ---------------------------------------- ---------- mg < > 1 ( 352 mg) : (EP) ( 70 mg) ---------------------------------------- ---------- mg : (EP) ( D3 5600 ) ---------------------------------------- ---------- mg < > 710, . < > 270, . 1 1 1 (70 mg/2800 IU 70 mg/5600 IU) , 30 ( ).

2 1 1 70 mg/5600 IU .. 4 .. 3~5 .. , , ( ). 30 . 399 2/11 (170 230 mL) . 30 .. ( ). D ( , 4. , 2) (4) ). D ( . 70 , , ) D.

3 D 25-hydroxyvitamin D . D 400 IU 800 IU . 1 400 IU 800 IU D . 1 1 1 . , 2 . (18 ): . (65 ): . : ( 35 60 mL/min) , ( 35 mL/min ) . 1.

4 , (170 230 mL) , . ( ).. , ( (Barrett's esophagus) ), , .. 2. 1) 2) 30 3) 4) (4. ) 5) , (galactose intolerance), Lapp (Lapp lactase deficiency) - (glucose- 399 3/11 galactose malabsorption) . 3. 1).

5 5 , . 8000 . 2) (1) 1 1 3 , , ( ; n=994) , 10 mg/day 196 % , 397 % . (n=6,459), 2 5 mg/day 1 2 10 mg/day 3,236 %, 3,223 % . %, % . 49~54 % , 54~89 % . , , 1 %.

6 , , 1 % / (FIT) *% (196 ) % (397 ) ** % (3,236 ) % (3,223 ) ( , , ) / 399 4/11 * 3 10 mg/day ** 2 5 mg/day, 1 2 10 mg/day . 1 10 mg/day.

7 5 mg 20 mg 401 . 2 , 5 mg 10 mg 296 3 . 10 mg/day 151 , 3 . (2) 1 1 70 1 1 (n=519) 10 1 1 (n=370) , 1 , , 1 % . , , 1 % 70 mg 1 1 % 10 mg 1 1 % ( , , ) 3) (1) , , ( 10 mg/day 2 70 mg, 1 1 1 ) 10 mg/day %, %, 70 mg, 1 1 %, %.

8 2 % , , 399 5/11 , . , , 2 % 2 1 10 mg, 1 1 % (146 ) % (95 ) 70 mg, 1 1 % (109 ) % (58 ) 4) (n=682) (n=35) 15 , , (70 mg/2,800 IU) 1 70 mg . (n=619) (n=33) 24 2,800 IU D3 (70 mg/2,800 IU) (70 mg/2,800 IU).

9 5) : .. (1) : . ( , , ) .. (2) : , , , , , , . (1. , 4. , ). / ( ) (4. ). (3) : , / , / (4. , 1) ). , (low-energy fracture) (4. , 1) ). (4) : , . (5) : ( ), , . - , (6) : , , , ( ) 6) 6 798 %(42 /798 , 43 ).

10 399 6/11 %(34 /798 , 35 ) , , %(10 /798 , 10 ), %(4 /798 , 4 ), %(3 /798 , 3 ), %(2 /798 , 2 ), , , , , , %(1 /798 , 1 ) . %(2 /798 , 2 ) . %(1 /798 , 1 ) . 4. 1) , . (1) , . (2) ( 35 mL/min ) (6. , , , , 5) ).