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Multiple Myeloma - Alberta Health Services

Bone lesions or osteopenia with compression fractures] or ROTI • High risk features including bone marrow plasmacytosis ≥ 60%, t(4;14) or p53 deletion, two or more focal bone lesions detected by CT, MRI, or PET scan, or ratio of involved/uninvolved free light chains > 100 . Staging

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