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Part 3. The Role of the Mobile Phase in Selectivity
For any reversed-phase method, the choice of acetonitrile or methanol will ... Choosing the correct buffer for HPLC method development can seem very intimidating due to the vast number of buffers available. ... increases stability to pH ~12. Buffer Selection for RP ‐ HPLC = Typical for LC/MS = Typical for LC/UV.
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