Product Catalog 2014 - Global - Phadia

1 - -ALLERGY & AUTOIMMUNITYP roduct Catalog 2014 - -- -All Phadia products mentioned herein are produced according to ISO 13485 of ContentsIntroduction 5 Available assays 6 Overview of instruments and assays 7 Allergy and asthma assays ImmunoCAP Total IgE 8 ImmunoCAP Total IgE low range 9 ImmunoCAP Specific IgE 0 ImmunoCAP Phadiatop / Phadiatop Infant ImmunoCAP Specific IgG ImmunoCAP Specific IgG4 ImmunoCAP Specific IgA 4 ImmunoCAP ECP 5 ImmunoCAP Tryptase 6 ImmunoCAP Allergen components 7 ImmunoCAP Allergens 9 ImmunoCAP Antigens ImmunoCAP Rapid 4 ImmunoCAP ISAC 5 Autoimmunity assays EliA 8 VarelisA 4 ImmunoCAP Thyroglobulin IgG / Thyroid Peroxidase IgG 4 ImmunoCAP Gliadin IgA/IgG 44 Phadia Laboratory Systems Phadia 5000 45 System reagents, Accessories and Software Phadia 500 46 System reagents, Accessories and Software Phadia 000 47 System reagents, Accessories and Software Phadia 50 48 System reagents, Accessories and Software Phadia 00 49 System reagents, Accessories and SoftwareQuality Club 50 Specifications 5 ImmunoCAP , EliA and VarelisA Page- 4 -- 5 -IntroductionAbout ImmunoDiagnosticsPhadia.

2 The Global leader in allergy and autoimmunity diagnostics, is now the ImmunoDiagnostics business of Thermo Fisher Scientific. As the ImmunoDiagnostics experts within Thermo Fisher Scientific, we work to dramatically improve the management of allergy, asthma and autoimmune disease. We do this by providing healthcare professionals with superior diagnostic technologies and clinical expertise. This results in better healthcare and quality of life for millions of patients and their families. For more information, please visit Thermo Fisher Scientific Inc. is the world leader in serving science. Our mission is to enable our customers to make the world healthier, cleaner and safer.

3 With revenues of $ billion, we have approximately 9,000 employees and serve customers within pharmaceutical and biotech companies, hospitals and clinical diagnostic labs, universities, research institutions and government agencies, as well as in environmental and process control industries. We create value for our key stakeholders through three premier brands, Thermo Scientific, Fisher Scientific and Unity Lab Services, which offer a unique combination of innovative technologies, convenient purchasing options and a single solution for laboratory operations management. Our products and services help our customers solve complex analytical challenges, improve patient diagnostics and increase laboratory 6 -Immunoglobulin E Phadiatop , Phadiatop Infant Allergy, atopy diagnosisTotal IgE Allergy diagnosisSpecific IgE Allergy, allergen-specific diagnosis, Molecular AllergologyImmunoglobulin A Specific IgA Allergy (food-sensitive enteropathies)

4 Gliadin IgA Celiac DiseaseImmunoglobulin G Specific IgG Allergy, celiac disease, immunotherapy, lung disease, autoimmunitySpecific IgG4 Allergy, immunotherapyGliadin IgG Celiac DiseaseThyroid Peroxidase IgG Thyroid autoimmunityThyroglobulin IgG Thyroid autoimmunityCellular Markers (Asthma and Inflammation) ECP Asthma, guiding corticosteroid treatmentTryptase Allergy, anaphylaxis, hematological disorders, immunotherapyAutoimmunityEliACCP, RF Rheumatoid arthritisACA, anti- GPI Antiphospholipid syndromeANA / ENA Connective tissue diseasesANCA, GBM VasculitisAnti-IgA ImmunodeficiencyAnti-M Primary liver cirrhosisAnti-TG, Anti-TPO Autoimmune thyroid diseaseCelikey, Gliadin Celiac diseaseCalprotectin , ASCA Inflammatory bowel diseasesVarelisAANA / ENA RheumatologyACA / GPI Antiphospholipid syndromeANCA, GBM VasculitisCelikey, Gliadin Celiac diseaseTG/TPO Thyroid diseasesLKM , M etc.

5 Liver diseases RapidSpecific IgE Allergy, allergen-specific diagnosisImmunoCAP ISACS pecific IgE Allergy, Molecular AllergologySpecific IgG4 Allergy, immunotherapyAvailable assays- 7 -Overview of instruments and assaysOverview of instruments and assays Phadia 100 Phadia 250 Phadia 1000 Phadia 2500 Phadia 5000 Allergy and Asthma assaysImmunoCAP Total IgE ImmunoCAP Total IgE Low Range ImmunoCAP Specific IgE ImmunoCAP Phadiatop/ Phadiatop Infant ImmunoCAP Specific IgA ImmunoCAP Specific IgG/IgG4 ImmunoCAP ECP ImmunoCAP Tryptase Autoimmunity assaysEliA ANA EliA ANCA/GBM EliA CCP EliA Celikey EliA Gliadin EliA Calprotectin EliA APS ImmunoCAP

6 Thyroglobulin IgG ImmunoCAP Thyroid Peroxidase IgG ImmunoCAP Gliadin IgA/IgG - 8 -Reagents Phadia 5000 / Phadia 2500 / Phadia 1000 / Phadia 250 Product Size Art. IgE Conjugate 100 6 x 100 10-9319-01 Total IgE Conjugate 400 6 x 400 10-9480-01 Total IgE Calibrator Strip 5 x 1 curve 10-9387-01 Total IgE Curve Control Strip 5 x 3 pairs 10-9325-01 Total IgE Anti-IgE ImmunoCAP 16 14-4509-01 IgE/ECP/Tryptase Sample Diluent 50 ml 10-9360-01 System reagents, see page 45-48 ControlImmunoCAP Total IgE Control LMH 3 x 2 x 4 10-9447-01 Reagents Phadia 100 Product Size Art. IgE (Conjugate, Curve Control, Anti-IgE) 96, 4CC, 6 x 16 10-9251-01 Total IgE (Conjugate, Curve Control) 96, 4CC 10-9517-01 Total IgE Calibrators 1 curve 10-9252-01 Total IgE Curve Controls 3 pairs 10-9257-01 Total IgE Anti-IgE ImmunoCAP 16 14-4509-01 IgE/ECP/Tryptase Sample Diluent 6 x ml 10-9256-01 System reagents, see page 49 ControlImmunoCAP Total IgE Control LMH 3 x 2 x 4 10-9447-01 Please note that all products are not available in all countries.

7 The article number s two digit suffix (-01) may vary between IgE & Total IgE Low RangeTotal IgE measures the quantitative amount of total IgE in human serum or plasma. IgE antibodies are produced by the body as a result of repeated allergenic Total IgE- 9 -ImmunoCAP Total IgE Low RangePlease note that all products are not available in all countries. The article number s two digit suffix (-01) may vary between Phadia 5000 / Phadia 2500 Product Size Art. No. Total IgE Low Range ImmunoCAP 3 x 16 14-4497-35 Specific IgE Conjugate 100 6 x 100 10-9316-01 Specific IgE Conjugate 400 6 x 400 10-9310-01 Specific IgE Calibrator Strip 5 x 1 curve 10-9459-01 Specific IgE Curve Control Strip 5 x 3 pairs 10-9312-01 IgE/ECP/Tryptase Sample Diluent 50 ml 10-9360-01 Specific IgE Anti-IgE ImmunoCAP 16 14-4417-01 System reagents, see page 45-46 Reagents Phadia 1000 / Phadia 250 Product Size Art.

8 No. Total IgE Low Range ImmunoCAP 3 x 16 14-4497-35 Specific IgE Conjugate 100 6 x 100 10-9316-01 Specific IgE Conjugate 400 6 x 400 10-9310-01 Specific IgE Calibrator Strip 5 x 1 curve 10-9459-01 Specific IgE Curve Control Strip 5 x 3 pairs 10-9312-01 IgE/ECP/Tryptase Sample Diluent 50 ml 10-9360-01 Specific IgE Anti-IgE ImmunoCAP 16 14-4417-01 System reagents, see page 47-48 Reagents Phadia 100 Product Size Art. No. Total IgE Low Range ImmunoCAP 3 x 16 14-4497-35 Specific IgE (Conjugate, Curve Controls) 96, 2 pairs CC 10-9462-01 Specific IgE Conjugate 6 x 96 10-9463-01 Specific IgE Calibrators 1 curve 10-9460-01 Specific IgE Curve Controls 3 pairs 10-9408-01 IgE/ECP/Tryptase Sample Diluent 6 x ml 10-9256-01 Specific IgE Anti-IgE ImmunoCAP 16 14-4417-01 System reagents, see page 49- 0 -Please note that all products are not available in all countries.

9 The article number s two digit suffix (-01) may vary between Phadia 5000 / Phadia 2500 Product Size Art. No. Specific IgE Conjugate 400 6 x 400 10-9310-01 Specific IgE Calibrator Strip 5 x 1 curve 10-9459-01 Specific IgE Curve Control Strip 5 x 3 pairs 10-9312-01 IgE/ECP/Tryptase Sample Diluent 50 ml 10-9360-01 Specific IgE Anti-IgE ImmunoCAP 16 14-4417-01 System reagents, see page 45-46 ControlsImmunoCAP Specific IgE Control 6 x 4 10-9449-01 ImmunoCAP Specific IgE f1 Control 4 x 4 10-9450-01 ImmunoCAP Specific IgE Negative Control 6 x 4 10-9445-01 ImmunoCAP Specific IgE Control L 6 x 4 10-9528-01 ImmunoCAP Specific IgE Control M 6 x 4 10-9529-01 ImmunoCAP Specific IgE Control H 6 x 4 10-9530-01 Allergens ImmunoCAP Allergens.

10 See pages 9- Reagents Phadia 1000 / Phadia 250 Product Size Art. No. Specific IgE Conjugate 100 6 x 100 10-9316-01 Specific IgE Conjugate 400 6 x 400 10-9310-01 Specific IgE Calibrator Strip 5 x 1 curve 10-9459-01 Specific IgE Curve Control Strip 5 x 3 pairs 10-9312-01 IgE/ECP/Tryptase Sample Diluent 50 ml 10-9360-01 Specific IgE Anti-IgE ImmunoCAP 16 14-4417-01 System reagents, see page 47-48 ControlsImmunoCAP Specific IgE Control 6 x 4 10-9449-01 ImmunoCAP Specific IgE f1 Control 4 x 4 10-9450-01 ImmunoCAP Specific IgE Negative Control 6 x 4 10-9445-01 ImmunoCAP Specific IgE Control L 6 x 4 10-9528-01 ImmunoCAP Specific IgE Control M 6 x 4 10-9529-01 ImmunoCAP Specific IgE Control H 6 x 4 10-9530-01 Allergens ImmunoCAP Allergens, see pages 9- Reagents Phadia 100 Product Size Art.