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Prophylactic antibiotic – timing and dosage

risk of the developement of bacterial resistance Classen D C, Evans R S, Pestotnik S L, Horn S D, Menlove R L, Burke J P. The timing of prophylactic administration of antibiotics and the risk of surgical-wound infection. N Engl J Med. 1992;326:281–286.

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  Risks, Surgical

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