Prostate Surgeries and Interventions

1 Prostate Surgeries and Interventions Page 1 of 21 UnitedHealthcare Commercial Medical Policy Effective 05/01/2022 Proprietary Information of UnitedHealthcare. Copyright 2022 United HealthCare Services, Inc. UnitedHealthcare Commercial Medica l Policy Prostate Surgeries and Interventions Policy Number: 2022T0618C Effective Date: May 1, 2022 Instructions for Use Table of Contents Page Coverage Rationale .. 1 Documentation Requirements .. 2 Applicable Codes .. 3 Description of Services .. 4 Clinical 4 Food and Drug 17 References .. 18 Policy History/Revision Information .. 21 Instructions for 21 Coverage Rationale Transurethral ablation of the Prostate is proven and medically necessary in certain circumstances. For medical necessity clinical coverage criteria, refer to the InterQual 2022, Apr.

2 2022 Release, CP: Procedures, Prostatectomy, Transurethral Ablation. Click here to view the InterQual criteria. Cryoablation of the Prostate is proven and medically necessary in certain circumstances. For medical necessity clinical coverage criteria, refer to the InterQual 2022, Apr. 2022 Release, CP: Procedures, Cryoablation, Prostate . Click here to view the InterQual criteria. Surgical prostatectomy is proven and medically necessary in certain circumstances. For medical necessity clinical coverage criteria, refer to the InterQual 2022, Apr. 2022 Release, CP: Procedures, Prostatectomy, Radical. Click here to view the InterQual criteria. Prostatic urethral lift (PUL) is proven and medically necessary when performed according to the following Food and Drug Administration (FDA) labeled indication: Treating symptoms due to urinary outflow obstruction secondary to benign prostatic hyperplasia (BPH), including lateral and median lobe hyperplasia.

3 In men 45 years of age or older, and The following are not present: o Prostate volume of > 100 cc o A urinary tract infection o Urethra conditions that may prevent insertion of delivery system into bladder o Urinary incontinence due to incompetent sphincter o Current gross hematuria Related Commercial Policies None Prostate Surgeries and Interventions Page 2 of 21 UnitedHealthcare Commercial Medical Policy Effective 05/01/2022 Proprietary Information of UnitedHealthcare. Copyright 2022 United HealthCare Services, Inc. High-energy water vapor thermotherapy for the treatment of malignant Prostate tissue is unproven and not medically necessary due to insufficient evidence of safety and/or efficacy. The transperineal placement of biodegradable material, peri-prostatic (via needle) is proven and medically necessary for use with radiotherapy for treating Prostate cancer.

4 The transperineal placement of biodegradable material, peri-prostatic (via needle) is unproven and not medically necessary for all other indications due to insufficient evidence of safety and/or efficacy. The following procedures are unproven and not medically necessary due to insufficient evidence of safety and/or efficacy: Transurethral waterjet ablation of the Prostate (aquablation) Focal laser ablation Insertion of a temporary prostatic urethral stent Vascular embolization Documentation Requirements CPT Codes* Required Clinical Information Prostate Surgeries and Interventions 52441 52442 53850 53852 55866 55873 55874 Medical notes documenting the following, when applicable: Transurethral Ablation Diagnosis History of the medical condition(s) requiring treatment or surgical intervention Documentation of signs and symptoms.

5 Including onset, duration, and frequency Physical exam, including result of digital rectal exam Relevant medical history, including list of all current patient medication Treatments tried, failed, or contraindicated; include the dates and reason for discontinuation Relevant surgical history, including dates Reports of all recent imaging studies and applicable diagnostics including: o Results of uroflow test (Q-max and postvoid residual (PVR) test) o Results of urinalysis o Results of PSA test o Results of Prostate biopsies Physician treatment plan Cryoablation of the Prostate Diagnosis, including: o Cancer risk group, including stage of disease o Life expectancy History of the medical condition(s) requiring treatment or surgical intervention Documentation of signs and symptoms, including onset, duration, and frequency Physical exam Relevant medical history Treatments tried, failed, or contraindicated.

6 Include the dates and reason for discontinuation Relevant surgical history, including dates Reports of all recent imaging studies and applicable diagnostics, including: o Results of Prostate volume via transrectal ultrasound (TRUS) o Results of PSA test Physician treatment plan Surgical - Radical Prostatectomy Diagnosis, including: o Results of diagnostic Prostate biopsy Prostate Surgeries and Interventions Page 3 of 21 UnitedHealthcare Commercial Medical Policy Effective 05/01/2022 Proprietary Information of UnitedHealthcare. Copyright 2022 United HealthCare Services, Inc. CPT Codes* Required Clinical Information Prostate Surgeries and Interventions o Cancer risk group, including stage of disease o Life expectancy History of the medical condition(s) requiring treatment or surgical intervention Documentation of signs and symptoms, including onset, duration, and frequency Physical exam Relevant medical history Treatments tried, failed, or contraindicated.

7 Include the dates and reason for discontinuation Relevant surgical history, including dates Reports of all recent imaging studies and applicable diagnostics, including results of PSA test Physician surgical plan, including plans for pelvic lymph node dissection Prostatic Urethral Lift (PUL) Diagnosis History of the medical condition(s) requiring treatment or surgical intervention Documentation of signs and symptoms, including onset, duration, and frequency; include presence of the following: o Urinary incontinence o Gross hematuria Physical exam Relevant medical history, including presence of the following: o Urinary tract infection o Allergy to nickel Treatments tried, failed, or contraindicated; include the dates and reason for discontinuation Relevant surgical history, including dates Reports of all recent imaging studies and applicable diagnostics, including: o Prostate volume o Presence of signs or symptoms of obstruction o Presence of protruding median lobe of the Prostate Physician treatment plan Transperineal Placement of Biodegradable Material Diagnosis History of the medical condition(s) requiring treatment or surgical intervention Relevant medical history Relevant surgical history, including dates Physician treatment plan including specifics of radiotherapy plan *For code descriptions, refer to the Applicable Codes section.

8 Applicable Codes The following list(s) of procedure and/or diagnosis codes is provided for reference purposes only and may not be all inclusive. Listing of a code in this policy does not imply that the service described by the code is a covered or non-covered health service. Benefit coverage for health services is determined by the member specific benefit plan document and applicable laws that may require coverage for a specific service. The inclusion of a code does not imply any right to reimbursement or guarantee claim payment. Other Policies and Guidelines may apply. CPT Code Description 0421T Transurethral waterjet ablation of Prostate , including control of post-operative bleeding, including ultrasound guidance, complete (vasectomy, meatotomy, cystourethroscopy, urethral calibration and/or dilation, and internal urethrotomy are included when performed) 0582T Transurethral ablation of malignant Prostate tissue by high-energy water vapor thermotherapy, including intraoperative imaging and needle guidance Prostate Surgeries and Interventions Page 4 of 21 UnitedHealthcare Commercial Medical Policy Effective 05/01/2022 Proprietary Information of UnitedHealthcare.

9 Copyright 2022 United HealthCare Services, Inc. CPT Code Description 0655T Transperineal focal laser ablation of malignant Prostate tissue, including transrectal imaging guidance, with MR-fused images or other enhanced ultrasound 37243 Vascular embolization or occlusion, inclusive of all radiological supervision and interpretation, intraprocedural road mapping, and imaging guidance necessary to complete the intervention: for tumors, organ ischemia, or infarction (when performed on Prostate tissue) 52441 Cystourethroscopy, with insertion of permanent adjustable transprostatic implant; single implant 52442 Cystourethroscopy, with insertion of permanent adjustable transprostatic implant; each additional permanent adjustable transprostatic implant (List separately in addition to code for primary procedure) 53850 Transurethral destruction of Prostate tissue; by microwave thermotherapy 53852 Transurethral destruction of Prostate tissue; by radiofrequency thermotherapy 53854 Transurethral destruction of Prostate tissue.

10 By radiofrequency generated water vapor thermotherapy 53855 Insertion of a temporary prostatic urethral stent, including urethral measurement 55866 Laparoscopy, surgical prostatectomy, retropubic radical, including nerve sparing, includes robotic assistance, when performed 55873 Cryosurgical ablation of the Prostate (includes ultrasonic guidance and monitoring) 55874 Transperineal placement of biodegradable material, peri-prostatic, single or multiple injection(s), including image guidance, when performed CPT is a registered trademark of the American Medical Association Description of Services Benign prostatic hyperplasia (BPH) is an enlarged Prostate and occurs most often during the second growth phase of the Prostate (around age 25 and up). As the Prostate enlarges, it presses against the urethra, which can result in the thickening of the bladder wall, the inability to empty the bladder fully, trouble starting urination, a week flow, urgency and needing to push or strain to urinate.