REFERENCE GUIDE FOR PHARMACY TECHNICIAN EXAM

1 REFERENCE GUIDE for PHARMACY TECHNICIAN 1 REFERENCE GUIDEFOR PHARMACYTECHNICIAN EXAMEDITION 2014-2015(Covers an updated 2013-PTCB Blue Print)MANAN SHROFFR eference GUIDE for PHARMACY TECHNICIAN 2 This REFERENCE GUIDE is not intended as a substitute for the advice of a physician. Students or readers mustconsult their physicians about any existing problem. Do not use any information in this REFERENCE GUIDE forany kind of self treatment. Do not administer any dose of mentioned drugs in this REFERENCE GUIDE withoutconsulting your physician. This is only a review GUIDE for preparation for the PHARMACY TECHNICIAN author of this REFERENCE GUIDE is not responsible for any kind of misinterpreted, incorrect or misleadinginformation or any typographical errors in this GUIDE . Any doubtful or questionable answers should bechecked in other available REFERENCE rights part of this GUIDE may be reproduced or transmitted in any form or by any means, electronically photo-copied, recorded or otherwise, without prior written permission of the is a registered trademark of PHARMACY Exam of Krishna Publication Inc.

2 Any unauthorizeduse of this trademark will be considered a violation of REFERENCE GUIDE is in no way authorized by or sponsored by the PHARMACY TECHNICIAN CertificationBoards, GUIDE for PHARMACY TECHNICIAN 3 Today, the PHARMACY is considered a very fast growing field. The jobs done by pharmacistsyesterday have completely changed today. Today s pharmacist is not merely a machine to dispensedrugs, he or she can counsel the patients, keep an eye on important interactions, and practice moretowards the clinical side of the field of , this requires a great amount of time and patience. By considering all of these factors, in1995 PTCB was introduced. By certifying PHARMACY technicians, pharmacists can spend moretime on patient counseling and other patient oriented prepare a PHARMACY TECHNICIAN to take over some of the responsibilities of pharmacists, such asdiscovering duplicated therapy, wrong doses and directions, and the knowledge of drug indicationsand interactions, the PHARMACY TECHNICIAN Certification Exam was introduced in exam will test PHARMACY technicians on three major areas:1.

3 Assisting the pharmacist in serving Maintaining medications and inventory control Participating in administration and management of the PHARMACY REFERENCE GUIDE has more than 500 questions that allow you to practice tackling theactual have also included more than 40 chapters that will give you knowledge of drug trade names,generic names, indications and major adverse PTCB exam puts more emphasis on calculations; therefore, all efforts were made to includecalculations in the practice test at the end of the REFERENCE GUIDE will ensure that you understand the materialprovided for you in this REFERENCE GUIDE . All suggestions from you are always of SHROFFPREFACER eference GUIDE for PHARMACY TECHNICIAN 4 TABLE OF CONTENTSSECTION -I1 INOTROPIC AGENTS72 ANTIARRHYTHMIC AGENTS73 BETA-BLOCKERS84 CENTRALLY ACTING ANTIHYPERTENSIVE95CA-CHANNEL BLOCKERS106 ACE INHIBITORS117 VASODILATORS128 ANTIPLATELET AGENTS129 CORONARY VASODILATORS1310 THROMBOLYTIC AGENTS1411 DIURETICS1412 SPECIFIC ALPHA-1 BLOCKERS1613 ANTIHYPERLIPIDEMIC AGENTS1714 TRANQUILIZERS1815 ANTIEPILEPTICS2016 ANTIDEPRESSANTS2117 ANTI PARKINSON S2518 ATTENTION DEFICIT DISORDER2819 ANTI NEUROLEPTICS3020 ANTIBIOTICS3221 ANTI-AIDS4422 ACNE PRODUCTS4623 PEPTIC ULCER4724 ANTIHISTAMINES4925 ARTHRITIS5026 ASTHMA5127 BPH5328 COLONY and ERYTHROCYTE STIMULATING FACTORS5429 HEMATINIC AGENTS5430 HYPERURICEMIA and GOUT5531 IMMUNOSUPPRESSANTS5632 MIGRAINE5733 NAUSEA

4 MEDICATIONS5934 NSAIDs61 REFERENCE GUIDE for PHARMACY TECHNICIAN 535 OPIOIDS ANALGESIC6236 OSTEOPOROSIS and HYPOCALCEMIA6537 ANTI PLATELETS and ANTI COAGULANTS6738 SMOKING CESSATION AIDS AGENTS6939 THYROID6940 ULCERATIVE COLITIS7041 DIABETES-RELATED DRUGS7142 PHARMACY LAW7543 PHARMACEUTICAL CALCULATIONS86 SECTION-II44 QUESTIONS9245 ANSWERS13646 PRACTICE TEST17747 ANSWERS189 REFERENCE GUIDE for PHARMACY TECHNICIAN 6 SECTION -IReference GUIDE for PHARMACY TECHNICIAN 71-INOTROPIC AGENTSB randGenericAdverse EffectsLanoxinDigoxinanorexia, nauseaPrimacorMilrinonethrombocytopeniaI nocorAmrinoneventricular arrhythmiaTherapeutic uses of inotropic agents:*Congestive heart failure (CHF)Terminology:Anorexia: Appetite : A low platelets count in arrhythmia: Irregular movements of left ventricles of the AGENTSM/A:This class of agents is indicated for the treatment of an irregular heart EffectsCordaroneAmiodarone pulmonary toxicityNorpaceDisopyramidedry eyes, blurred vision, negative inotropic effectTambocorFlecainide node suppressionEthmozineMoricizine node suppressionXylocaineLidocaine CNS stimulation, seizureTonocardTocainide pulmonary toxicityDilantinPhenytoin gingival hyperplasia, ataxiaCerebyxProcanbidProcainamide , blood dyscrasiaQuinidineQuinidine diarrheaReference GUIDE for PHARMACY TECHNICIAN 8 Therapeutic uses of antiarrhythmic agents:*ArrhythmiaTerminology:Pulmonary toxicity: Lung hyperplasia: Gum inflammation and : Lack of coordination of muscle : Rapid involuntary movement of eyes that may be from side to side, up and down.

5 Systemic lupus erythematosus (chronic inflammatory disease of connective tissues).Blood dyscrasia: Abnormality in node suppression: Slowing down in conduction velocity of inotropic effects: Reducing the force of muscle contraction of :They block Beta-1 receptors in cardiac tissues. They reduce the oxygen requirement of the heart bydecreasing the heart rate and force of contraction of the heart associated with an EffectsTenorminAtenololbradycardiaLopres sorMetoprololbradycardiaToprol XLInderalPropranololbradycardiaCorgardNa dololbradycardiaZebetaBisoprololbradycar diaNormodyneLabetalolbradycardiaTrandate SectralAcebutololbradycardiaCoregCarvedi lolbradycardiaBreviblocEsmololbradycardi aLevatolPenbutololbradycardiaReference GUIDE for PHARMACY TECHNICIAN 9 Therapeutic uses of beta-blockers:*Hypertension and anginaDo not use beta-blockers for:1.

6 CHF patients: May cause fatal heart Diabetic patients: May mask the symptoms of Asthma patients: May constrict the bronchial smooth muscles by blocking beta-2 :Bradycardia: Slowing down of heart : Low blood glucose muscles: Smooth muscles of : Heart disorder with sharp pain in ACTING ANTIHYPERTENSIVE AGENTSM/A:Agents of this class generally inhibit the secretion of nor-adrenaline from the brain, which isresponsible for causing EffectsAldometMethyldopahemolytic anemiaCatapresClonidinehypotensionTenexG uanfacinehypotensionWytensinGuanabenzhyp otensionTherapeutic uses:*HypertensionTerminology:Hemolytic anemia: In hemolytic anemia, due to a premature destruction of RBCs, there are not enoughred blood cells in : Elevation of arterial blood pressure above the normal : Condition in which arterial blood pressure is abnormally GUIDE for PHARMACY TECHNICIAN 105-CA-CHANNEL BLOCKERSM/A:They produce the dilation of coronary arteries, and thereby increase the blood flow to the EffectsAdalatNifedipinehypotensionProcar diaCalanVerapamilhypotension, constipationIsoptinVerelanCardizemDiltia zemhypotensionNorvascAmlodipinehypotensi onPlendilFelodipinehypotensionCardeneNic ardipinehypotensionDynaCircIsradipinehyp otensionVascorBepridilhypotensionNimotop NimodipinehypotensionSularNisoldipinehyp otensionTherapeutic uses:*HypertensionTerminology:Hypertensi on: Elevation of arterial blood pressure above the normal : Condition in which arterial blood pressure is abnormally GUIDE for PHARMACY TECHNICIAN 116-ACE INHIBITORSM/A.

7 They inhibit the enzymatic conversion of angiotensin I to angiotensin II. They are known as angio-tensin converting enzyme inhibitors (ACE inhibitors).BrandGenericAdverse EffectsVasotecEnalaprilhypertension, dry cough, dysgeusia, hyperkalemiaZestrilLisinoprilhypertensio n, dry cough, dysgeusia, hyperkalemiaPrinivilCapotenCaptoprilhype rtension, dry cough, dysgeusia, hyperkalemiaAltaceRamiprilhypertension, dry cough, dysgeusia, hyperkalemiaLotensinBenazeprilhypertensi on, dry cough, dysgeusia, hyperkalemiaAccuprilQuinaprilhypertensio n, dry cough, dysgeusia, hyperkalemiaMonoprilFosinoprilhypertensi on, dry cough, dysgeusia, hyperkalemiaMavikTrandolaprilhypertensio n, dry cough, dysgeusia, hyperkalemiaANGIOTENSIN II RECEPTOR ANTAGONISTSM/A: Angiotensin II receptor antagonists, also known as angiotensin receptor blockers (ARBs), are medi-cations that block the action of angiotensin II by preventing angiotensin II from binding to angiotensin IIreceptors on blood EffectsCozaarLosartanhyperkalemiaDiovanV alsartanhyperkalemiaAvaproIrbesartanhype rkalemiaAtacandCandesartanhyperkalemiaMi cardisTelmisartanhyperkalemiaThe advantage of ACE II receptor antagonists over ACE inhibitors is that they do not produce dry uses:*HypertensionReference GUIDE for PHARMACY TECHNICIAN 12 Terminology:Dysgeusia: Loss of : An elevated concentration of potassium in.

8 As the name suggests, this class of agents generally causes dilation of blood , tachycardia, peripheral neuritisLonitenMinoxidilhypertrichosis, tachycardiaRogaineHyperstatDiazoxideedem a, tachycardiaTherapeutic uses:*HypertensionTerminology:Tachycardi a: It typically refers to a heart rate that exceeds the normal range for a resting heartrate (heartratein an inactive or sleeping individual).Edema: An excessive accumulation of fluid in body : An excessive hair growth on the lupus erythematosus (SLE): It is a chronic, inflammatory autoimmune disorder. It may affectthe skin, joints, kidneys and other neuritis: It is a problem with the nerves that carry information to and from the brain and spinalcord. This can produce pain, loss of sensation and an inability to control AGENTSM/A:They generally inhibit the aggregation of platelets and make blood thinner in order to reduce EffectsEcotrinAspirin GI ulcer, bleedingTiclidTiclopidine bleeding, agranulocytosisPersantineDipyridamole bleedingPlavixClopidogrel bleedingReference GUIDE for PHARMACY TECHNICIAN 13 BrandGenericAdverse EffectsAggrenoxAspirin +bleedingDipyridamoleEffientPrasugrelble edingTherapeutic uses:*Heart strokes :Agranulocytosis: A disorder in which there is an acute deficiency of granulocytes in VASODILATORSM/A.

9 Agents of this class generally dilate the blood vessels of the heart, thereby help controlling hyper-tension and preventing an EffectsIsordilIsosorbide- lightheadedness, hypotension, severe headachesdinitrateSorbitrateIso-bidDilat rateNitrostatNitroglycerinelightheadedne ss, hypotension, severe headachesNitro durNitro-bidDeponitNitrolingualImdurIsos orbide-lightheadedness, hypotension, severe headachesISMO mononitrateMonoketTherapeutic uses:*AnginaTerminology:Lightheadedness: Dizziness (lightheadedness) is often caused by a decrease in blood supply to the : Condition in which an arterial blood pressure is abnormally GUIDE for PHARMACY TECHNICIAN 1410-THROMBOLYTIC AGENTSM/A:Agents of this class help removing a blood clot that usually occurs after a heart EffectsStreptaseStreptokinasesevere bleeding, intracranial hemorrhageAbbokinaseUrokinasesevere bleeding, intracranial hemorrhageKinlyticActivaseAlteplasesever e bleeding, intracranial hemorrhageTnkaseTenecteplasesevere bleeding, intracranial hemorrhageRetavaseReteplasesevere bleeding, intracranial hemorrhageTherapeutic uses:*Removal of a blood clot that usually occurs after a heart :Intracranial hemorrhage: An intracranial hemorrhage is a hemorrhage, or bleeding, within the :They generally increase the excretion of water from the body to reduce high blood pressure, swell-ing and Diuretics.

10 BrandGenericAdverse EffectsHydroDiurilHCTZ hypokalemiaOreticEsidrixDiurilChlorothia zide hypokalemiaZaroxolynMetolazone hypokalemiaLozolIndapamide hypokalemiaHygrotonChlorthalidonehypokal emiaReference GUIDE for PHARMACY TECHNICIAN 15 Loop Diuretics:BrandGenericAdverse EffectsLasixFurosemidehypokalemiaBumexBu metanidehypokalemiaDemadexTorsemidehypok alemiaEdecrinEthacrynic acidhypokalemia*Loop and thiazide diuretics generally cause hypokalemia; therefore, a potassium supplement isrequired when a patient is treated with the above :Hypokalemia: Low concentration of potassium in : It is th