START SAVING TODAY PAY AS LOW AS 0 BYDUREON BCise …

1 PAY AS LOW AS $0 EVERY MONTH* eligible commercially insured PATIENTSBYDUREON BCiseSavings CardPowered By: CHANGE HEALTHCARE*See reverse side for eligibility. Restrictions BCise is a registered trademark of the AstraZeneca group of companies. 2021 AstraZeneca. All rights reserved. US-49286 1/21 Please see accompanying full Prescribing Information including Boxed WARNING. BIN#PCN#GRP# ID# BY USING THIS CARD, YOU AND YOUR PHARMACIST UNDERSTAND AND AGREE TO COMPLY WITH THESE ELIGIBILITY REQUIREMENTS AND TERMS OF SAVING TODAYELIGIBLE commercially insured PATIENTSPAY A SLOW ASEVERY MONTH*$0 WITH YOUR PRESCRIPTION FOR BYDUREON BCiseELIGIBILITY: You may be eligible for this offer if you are insured bycommercial insurance and your insurance does not cover the full cost of your prescription, or you are not insured and are responsible for the cost of your prescriptions. Patients who are enrolled in a state or federally funded prescription insurance program are not eligible for this offer.

2 This includes patients enrolled in Medicare Part D, Medicaid, Medigap, Veterans Affairs (VA), Department of Defense (DOD) programs or TriCare, and patients who are Medicare eligible and enrolled in an employer-sponsored group waiver health plan or government-subsidized prescription drug benefit program for retirees. If you are enrolled in a state or federally funded prescription insurance program, you may not use this savings card even if you elect to be processed as an uninsured (cash-paying) patient. This offer is not insurance, is restricted to residents of the United States and Puerto Rico, and to patients over 18 years of age. If you use a mail-order pharmacy, please contact your pharmacy provider to confirm if this offer will be accepted. TERMS OF USE: eligible commercially insured patients with a validprescription for BYDUREON BCise (exenatide extended-release) injectable suspension 2 mg who present this savings card at participating pharmacies may pay as low as $0 per 28-day supply maximum savings limit applies; patient out-of-pocket expense may vary.

3 If you pay cash for your prescription, AstraZeneca will pay up to the first $150, and you will be responsible for any remaining balance, for each monthly prescription. Other restrictions may apply. Patient is responsible for applicable taxes, if any. Non-transferable, limited to one per person, cannot be combined with any other offer. Void where prohibited by law, taxed or restricted. Patients, pharmacists, and prescribers cannot seek reimbursement from health insurance or any third party for any part of the benefit received by the patient through this offer. AstraZeneca reserves the right to rescind, revoke, or amend this offer, eligibility and terms of use at any time without notice. This offer is not conditioned on any past, present or future purchase, including refills. Offer must be presented along with a valid prescription at the time of purchase. For additional details regarding this offer, please visit If you have any questions regarding this offer, please call USING THIS CARD, YOU AND YOUR PHARMACIST UNDERSTAND AND AGREE TO COMPLY WITH THESE ELIGIBILITY REQUIREMENTS AND TERMS OF Instructions for a Patient with an eligible Third Party: For insured /Covered Patients: Submit the claim to the primaryThird-Party Payer first, then submit the balance due to CHANGE HEALTHCARE as a Secondary Payer COB with patient responsibilityamount and a valid Other Coverage Code of 8.

4 This will reduce the eligible patient s out-of-pocket costs to as low as $0 per 28-day supply for BYDUREON BCise (exenatide extended-release) injectable suspension 2 mg subject to a maximum savings limit for the program, patient out-of-pocket expenses may vary. Reimbursement will be received from CHANGE Instructions for insured /Not Covered Patients: Submit theclaim to the primary Third-Party Payer first, if the primary claim submission shows a managed care restriction (step-edit, prior authorization, or NDC block), continue the claim adjudication process and submit the balance due to CHANGE HEALTHCARE as a Secondary Payer COB with patientresponsibility amount and a valid Other Coverage Code of 3. This will reduce eligible patient s out-of-pocket costs by $150 per 28-day supply. Reimbursement will be received from CHANGE Instructions for a Cash-Paying Patient: Submit this claim toCHANGE HEALTHCARE. A valid Other Coverage Code (eg, 1) is card will cover up to $150 per 28-day supply.

5 Reimbursement will be received from CHANGE HEALTHCARE. Valid Other Coverage CodeRequired. For any questions regarding CHANGE HEALTHCARE onlineprocessing, please call the Help Desk at click here for Medication Guide, and click here for Full Prescribing Information for BYDUREON may report side effects related to AstraZeneca products by clicking you are without prescription coverage and cannot afford your medication, AstraZeneca may be able to help. If you would like additional information regarding AstraZeneca products, please contact the Information Center at AstraZeneca in the US at 1-800-236-9933, Monday through Friday, 8am to 8pm ET, excluding holidays, or visit BCise is a registered trademark of the AstraZeneca group of managed by ConnectiveRx, on behalf of AstraZeneca. Product dispersed pursuant to program rules and federal and state laws. 2021 AstraZeneca. All rights reserved. US-53715 Last Updated 6/21 This product information is intended for US consumers