Tissue Reinforcement Solutions - Medicommers Kft.

1 TissueReinforcementSolutionsOne source for all your surgical mesh your local ETHICON Products representative for information on our physiologically-matched range of lightweight meshes andhernia devices or other Tissue Reinforcement Solutions . You canalso visit our website at source for all your surgical mesh your local ETHICON Products representative for information on our physiologically-matched range of lightweight meshes and hernia devices or other Tissue Reinforcement Solutions . You can also visit our website at Reinforcement SolutionsConfidence in your hands1 Tissue Reinforcement SolutionsConfidence in your handsMERSILENE meshPliable polyester mesh for the repair ofabdominal wall fascial defectsPROLENE meshClinically-proven polypropylene mesh for the repair of abdominal wall fascial defectsVYPRO meshPliable lightweight multifilament mesh forincisional hernia repairVYPRO IImeshLightweight multifilament mesh for open &laparoscopic inguinal hernia repairPROLENE3D PatchOne-piece low-profile hernia device for therepair of small abdominal wall herniasPROLENEH ernia SystemUnique 3-in-1 hernia device for the combinedanterior & posterior repair of groin herniasVICRYL meshAbsorbable mesh for temporary wound or organ supportPROCEEDS urgical MeshMulti-layer Tissue separating mesh for open &laparoscopic incisional hernia repairULTRAPRO meshLightweight monofilament mesh for abdominal wall reinforcementOne

2 Source for all your surgical mesh needs2 All three sizes are packed in flat, easy-to-store boxes with patient tracking ( ) (10cm) ( ) ( ) ( )Onlay PatchConnectorUnderlay PatchPROLENE* Hernia SystemPolypropylene MeshUnique 3-in-1 hernia device for the combinedanterior & posterior repair of groin herniasAvailable in three sizesProduct Code - PHSM(Medium) 3 per ( ) (10cm) ( ) ( ) (10cm)Onlay PatchConnectorUnderlay PatchProduct Code -PHSL(Large) 3 per ( ) ( ) ( ) ( ) (10cm)Onlay PatchConnectorUnderlay PatchProduct Code -PHSE(Extended) 3 per box2. ConnectorSits in internal ring or overlay patch tounderlay for Underlay PatchShould be deployed, pre-peritoneally, afterinsertion to provide a posterior three-in-one design1. Onlay PatchProvides a patch for the floor of the inguinal canalproviding the security of conventional mesh deployedOnly PatchUnderlay not deployedPROLENE* 3D PatchPolypropylene MeshAvailable with either Medium or Large underlayProduct Code - 3 DPM(Medium) 3 per deployedOnly Patchwith pre-shaped overlayUnderlay not deployedProduct Code - P3 DPM(Medium) 3 per deployedOnly PatchUnderlay not deployedProduct Code - 3 DPL(Large) 3 per deployedOnly Patchwith pre-shaped overlayUnderlay not deployedProduct Code - P3 DPL(Large) 3 per boxOne-piece low-profile herniadevice for the repair of smallabdominal wall herniasPre-shaped overlay to accomodate cord-structures All three sizes are packed in flat, easy-to-store boxes with patient tracking partly absorbable lightweightmonofilamentmesh composed ofapproximately equal parts of.

3 PROLENE* non-absorbable polypropylene MONOCRYL* absorbable poliglecaprone Mass of ULTRAPRO* (permanent polypropylene) is just 28g/m2compared to 80-85g/m2for PROLENE* mesh More than 60% less remaining foreign body meterial permanentlyimplantedArea weight ThicknessPore sizePmaxmmHgTension% strength@ 16 N/cmPROLENE*80-85 *128 handling characteristics MONOCRYL* poliglecaprone fibres used to stiffen the meshstructure for easier handling during the operation ULTRAPRO* mesh can be easily cut to shapeULTRAPRO* mesh6cm x 11cm10cm x 12cm10cm x 15cm15cm x 15cm15cm x 30cm30cm x 30cm3 per box3 per box3 per box3 per box1 per box1 per boxUMS3 UMP3 UMN3 UMM3 UMT1 UML1 PackagingCodeDimensions51. Polypropylene part remaining after a thin, bioresorbable fabric layer that effectively separatesits strong, supportive mesh from underlying Tissue and composite of proven products from ETHICON, PROCEED* SurgicalMesh addresses the issues of Tissue attachment, infection, andsub-optimal handling that remain potential problems with currentlyavailable Tissue separating PROLENE* Soft Mesh- Designed for strength, durability, and adaptibility Oxidized regenerated cellulose (ORC) fabric- Minimizes Tissue attachment Absorbable polydioxanone (PDS)

4 - Bonds the ORC to the mesh1 per box1 per box1 per box1 per box1 per box1 per box1 per boxPCDM1 PCDG1 PCDH1 PCDJ1 PCDT1 PCDW1 PCDL1 PROCEED*Surgical MeshPackagingCodeDimensionsPROCEED* Surgical MeshMulti-layer Tissue separating mesh foropen & laparoscopic incisional hernia repair15cm x 15cmsquare15cm x 20cmOval20cm x 25cmOval20cm x 30cmRectangular26cm x 34cmOval25cm x x * II meshVYPRO* II mesh is a partly absorbable lightweight multifilamentmesh, composed of approximately equal parts of: PROLENE* non-absorbable polypropylene. VICRYL* absorbable polyglactin. For all tension-free inguinal hernia repair techniques. Easy to cut, manipulate and place. Multidirectional flexibility and permanent stability in one. More than 60% less foreign body material compared toPROLENE* mesh. Long-lasting mutual integration achieved with improvedconnective scar Tissue formation compared to smallpore polypropylene mesh. 90 dayspost-implantation.

5 Fold development(in-vivo study)Lightweight VYPRO* II mesh. 90 dayspost-implantation. Fold-free incorporation(in-vivo study)6cm x 11cm12cm x 10cm15cm x 10cm15cm x 15cm3 per box3 per box3 per box3 per boxPVM2S3 PVM2P3 PVM2N3 PVM2M3 PackagingCodeDimensionsLightweight multifilament mesh for open& laparoscopic inguinal hernia repair7external oblique muscleinternal oblique muscletransversus abdominis musclerectus musclefascia transversalisVYPRO* meshperitoneumrectus muscle VYPRO mesh is placed preperitoneally as a sublay. Direct contact between the mesh and intraperitoneal structuresmust be avoided by using intact * mesh is available in several sizes. The size of the implantshould allow for a 5cm overlap of the fascial defect on all * meshPliable lightweight multifilamentmesh for incisional hernia repair30cm x 30cm15cm x 15cm10cm x 15cm1 per box1 per box1 per boxPVML1 PVMM1 PVMN1 PackagingCodeDimensions8 ETHICON Tissue Reinforcement ProductsCodeDescriptionTS54S30cm x 30cmPackaging1 sheet per boxCodeDescriptionPML130cm x 30cmPackaging1 sheet per boxPMM315cm x 15cm3 sheets per boxPMN315cm x 10cm3 sheets per boxPMR315cm x sheets per boxPMS36cm x 11cm3 sheets per x x 34cmRenal prosthesis 18cm x 10cmSplenic prosthesis 26cm x 30cm1 sheet per boxCodeDescriptionPackagingVICRYLMeshSyn thetic AbsorbableUndyed Knitted MeshMERSILENEMeshInterlocked Polyester FibrePROLENEMeshKnitted Polypropylene FibreVM102 Renal prosthesis18cm x x prosthesis26cm x 30cm9 VICRYL MEMBRANEA bsorbable Periodontal MembraneAbsorbable VICRYL membranesfor guided Tissue Buccal/Lingual membrane

6 With one VICRYL Ligature8mm Buccal/Lingual membrane with one VICRYL Ligature5mm Interproximal membrane with two VICRYL Ligatures10mm x 20mm membrane30mm x 35mm membrane1 per boxVPM29421 per boxVPM29451 per boxVPM29501 per boxVPM29521 per x 30mm x x 30mm x x 40mm x x 40mm x x 30mm x x 40mm x 50mmPDS PlatePDS PlatePDS PlatePDS PlatePDS Plate with perforationsPDS Plate with perforationsPDSP lates (poly-p-dioxanone) Synthetic absorbable implant for orbital floor x 30mm x x 30mm x x 40mm x x 40mm x x 30mm x x 40mm x 50mm3 packs per box3 packs per box3 packs per box3 packs per box3 packs per box3 packs per x 30mm x x 30mm x x 40mm x x 40mm x x 30mm x 40mmwith x 40mm x 50mmwith perforationsETHICON Tissue Reinforcement ProductsPDS PlatesVPM2940 VPM2942 VPM2945 VPM2950 VPM295210 Capitalised product names are trademarks of 08 2004