Transcription of クラスリン依存的エンドサイトーシスにおける細胞膜形 Title …
1 RIGHT:URL:CITATION:AUTHOR(S):ISSUE DATE: Title : ( Digest_ ) , , .. , 2017, ( )2017-03-23 9 2 ; 2021-06-08 1 .. 3 .. 5 1 .. 6 .. 7 CME .. 7 .. 8 .. 11 .. 13 2 .. 16 .. 17 .. 17 .. 17.
2 18 .. 23 .. 23 .. 23 .. 24 .. 25 .. 25 .. 26 .. 27 .. 38 2 3 .. 40 4 .. 43 .. 46 .. 52 3 10
3 RNAi Arp2/34 Arp2/3 5 AFM Atomic Force Microscopy CME Clathrin-Mediated Endocytosis CCP Clathrin Coated Pit Jasp Jasplakinolide Cyto Cytochalasin B Cytochalasin B EM Electron Microscope TIRF Total Internal Reflection Fluorescence microscope 6 1 7
4 1 2,3 CME Clathrin-Mediated Endocytosis, CME 1969 EM Kanaseki Kadota The Vesicle in a basket 4 1975 Pearse 5 42 CME 6 CME Clathrin-Coated Pit.
5 CCP 5 1 1-1 40 CME 8 CCP CCP TIRF 7 FCHO AP2 Auxilin GAK CME 1-1 CCP 2 1 F-BAR epsin N-BAR 4 5 CCP AP-2 epsin CCP CCP GTP Synaptojanin GAK CME i)
6 1960 1975 X Triskelion9 3 3 3 8 10 10,11 in vitro AP-2 epsin 12,13 1-1 ii) BAR Bin-amphiphysin-Rvs167 BAR in vitro Amphiphysin BAR BAR BAR 14,15 BAR in vitro F-BAR I-BAR N- BAR 3 16 CME F-BAR FCHO1 FCHO2 CME N- BAR Endophilin Amphiphysin SNX9 1-2 iii)
7 Epsin Epsin1 ENTH 13 ENTH in vitro in vivo CCP 17 10 1-2 iv) GTPase GTP 18 1989 Richard Vallee 19 in vitro in vivo shibire 20 Shibire 20 GTP S 21 21 in vitro PH 22 GTP 16 nm
8 8 nm 22 De Camilli GTP TIRF 23 CCP CME 1-2 24,25 v) 11 CME 1996 GFP CME 26,27 CCP 28,29 CME CME 30,31 CME 31 2011 CCP Arp2/3 32 CME CCP 33 CCP N-WASP cortactin Arp2/3 1-1 34.
9 35 Hip1R BAR SNX9 CCP 36 38 CME 1950 39 41 1960 12 Coated vesicle 4,42 CME 1975 5 1980 CME BAR epsin in vitro in vivo CME 1989 in vitro GTPase GTP 22 in vivo CCP in vitro in vivo
10 CME 13 / CME 14 1-1 CME Harvey T.
