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エストロゲンと血管 - UMIN
のHERS（Heart and Estrogen/progestin Replacement Study）[3]と2002年に発表されたWHI（Women’s Health Initiative）[4]であった．これらの報告は，そ れまでの予想とは大きく異なり，閉経後女性にエストロ ゲンに加えて黄体ホルモンであるプロゲスチンを併用投
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