Coupling Reagents - Bachem

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NHCOOHRHC PG1NH2COORHC PG2NHCORHC PG1NHCOORHC PG2COUPLINGREAGENTSCoupling Reagents2COUPLING Reagents AND ADDITIVES OFFERED BY BACHEMThe Coupling reaction the formation of an amide bond between amino acids and/or peptides is the crucial step in peptide synthesis. The reaction consists of two con-secutive steps:1. Activation of the carboxy moiety2. Acylation of the amino groupDuring the first step the protected amino acid (or pep-tide) reacts with a so-called Coupling reagent yielding a reactive intermediate. The chemistry behind and the most important Coupling Reagents will be presented in this brochure. PEPTIDE SYNTHESISOur comprehensive offer of Coupling Reagents , amino acids derivatives and further building blocks, and resins at will fulfill the needs of solid-phase and solution peptide synthesis. If the product you need is lacking, please let us know. Activation during Peptide SynthesisThe formation of an amide bond between a carboxylic acid moiety and an amino func-tion of two amino acids is the core reaction in peptide synthesis: could be isolated if desired.

Coupling Reagents 2. COUPLING REAGENTS AND . ADDITIVES OFFERED BY BACHEM. The coupling reaction i.e. the formation of an amide bond . between amino …

  Grantee, Coupling, Coupling reagents