Transcription of Coupling Reagents - Bachem
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Coupling Reagents - Bachem
NHCOOHRHC PG1NH2 COORHC PG2 NHCORHC PG1 NHCOORHC PG2 COUPLINGREAGENTSC oupling Reagents2 Coupling Reagents AND ADDITIVES OFFERED BY BACHEMThe Coupling reaction the formation of an amide bond between amino acids and/or peptides is the crucial step in peptide synthesis. The reaction consists of two con-secutive steps:1. Activation of the carboxy moiety2. Acylation of the amino groupDuring the first step the protected amino acid (or pep-tide) reacts with a so-called Coupling reagent yielding a reactive intermediate. The chemistry behind and the most important Coupling Reagents will be presented in this brochure. PEPTIDE SYNTHESISOur comprehensive offer of Coupling Reagents , amino acids derivatives and further building blocks, and resins at will fulfill the needs of solid-phase and solution peptide synthesis. If the product you need is lacking, please let us know. Activation during Peptide SynthesisThe formation of an amide bond between a carboxylic acid moiety and an amino func-tion of two amino acids is the core reaction in peptide synthesis: could be isolated if desired.
Coupling Reagents 2. COUPLING REAGENTS AND . ADDITIVES OFFERED BY BACHEM. The coupling reaction i.e. the formation of an amide bond . between amino …
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