Transcription of 2.2. PHYSICAL AND PHYSICOCHEMICAL METHODS
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2.2. PHYSICAL AND PHYSICOCHEMICAL METHODS
EUROPEAN PHARMACOPOEIA Clarity and degree of opalescence of PHYSICAL ANDPHYSICOCHEMICALMETHODS01/2008 CLARITY AND DEGREE OFOPALESCENCE OF LIQUIDSVISUAL METHODU sing identical test-tubes of colourless, transparent, neutralglass with a flat base and an internal diameter of 15-25 mm,compare the liquid to be examined with a referencesuspension freshly prepared as described below, the depthof the layer being 40 mm. Compare the solutions in diffuseddaylight 5 min after preparation of the reference suspension,viewing vertically against a black background. The diffusionof light must be such that reference suspension I canreadily be distinguished fromwater R, and that referencesuspension II can readily be distinguished from referencesuspension its clarity is the same as thatofwater Ror of the solvent used when examined under theconditions described above, or if its opalescence is not morepronounced than that of reference sus
2.2.2. Degree of coloration of liquids EUROPEAN PHARMACOPOEIA 6.0 made lie in the range of 1750-2000 NTU. Linearity must be demonstrated by constructing a calibration curve using at
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