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ACG Clinical Guideline: Nutrition Therapy in the …

Nature publishing group1 2016 by the american College of Gastroenterology The american Journal of GASTROENTEROLOGYPRACTICE guidelines INTRODUCTION Th e modern era of Clinical Nutrition began with the develop-ment of total parenteral Nutrition (PN) by Dudrick ( 1 ) in 1966, suggesting for the fi rst time that clinicians could compensate for intestinal failure with the potential to supply nutrients to any hospitalized patient. Further support for the unique contribution of PN came from a paper entitled Th e Skeleton in the Hospital Closet by Butterworth ( 2 ), which indicated that nearly 50% of patients in an urban hospital setting (in the United States) were malnourished. Th e response to these innovative concepts spurred the growth of Nutrition support teams and PN-based Therapy over the next two decades with the primary objective being to maintain lean body mass, achieve nitrogen balance, and prevent malnutri-tion ( 3 ).

McClave et al. The American Journal of GASTROENTEROLOGY VOLUME XXX | XXX 2016 www.amjgastro.com 2 moderate glucose …

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