Transcription of Acinetobacter baumanii multirresistente - seq.es
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Acinetobacter baumanii multirresistente - seq.es
2612 Rev Esp Quimioter 2010;23(1):12-19 Multidrug resistant Acinetobacter baumanii :clinical update and new highlightsABSTRACTThe role of multidrug resistant Acinetobacter bauma-niiand its clinical relevance have been recently appre-ciated as a ubiquitous opportunistic nosocomial patho-gen. Risk factors associated with A. baumaniiinfectioninclude severe underlying diseases, previous surgery, in-vasive procedures, treatment with broad-spectrum anti-biotics, length of hospital stay, admission to intensivecare units (ICU).Carbapenem-multidrug resistant A. baumaniiinfec-tions are probably associated to greater severity and mo-re complications; in our cohort mortality was andrelated mortality (within 72 hours) was Howe-ver, severe underlying diseases probably play an impor-tant role in the clinical outcome of patients with MDR-CA. baumaniiinfection and controversy exists regardingthe real mortality attributable to antimicrobial resistancebecause a high proportion of deaths took place > 7 daysafter diagnosis.
Acinetobacter se ha incrementado de manera sustancial, proba- blemente en relación a la relativa impermeabilidad de su mem-brana externa y la exposición ambiental a un amplio grupo de genes de resistencia1. Meropenem y, especialmente imipenem, suponen el trata-
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