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Alcohol and Medication Interactions

Alcohol and MedicationInteractionsRon Weathermon, , and David W. Crabb, medications can interact with Alcohol , thereby altering the metabolism or effects ofalcohol and/or the Medication . Some of these Interactions can occur even at moderatedrinking levels and result in adverse health effects for the drinker. Two types of Alcohol - Medication Interactions exist: (1) pharmacokinetic Interactions , in which Alcohol interfereswith the metabolism of the Medication , and (2) pharmacodynamic Interactions , in whichalcohol enhances the effects of the Medication , particularly in the central nervous system( , sedation).

Acetaldehyde, which is a toxic sub-stance that may contribute to many of alcohol’s adverse effects, is broken down further by an enzyme called 2Low alcohol doses are defined here as 0.3 g per kilogram body weight, equivalent to approximately two standard drinks for a person weighing 70 kg. Figure 2 Alcohol metabolism in the liver.

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  Alcohols, Acetaldehyde

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