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Chromosomes, Karyotyping, and Abnormalities

1 Chromosomes, Karyotyping, and Abnormalities (Learning Objectives) Learn the components and parts of a metaphase chromosome . Define the terms karyotype, autosomaland sex chromosomes. Explain how many of each is present in a gamete and in a somatic cell. Explain the field of cytogeneticsand its uses for visualization of chromosomes, karyotypingfor prenatal and postnatal diagnoses, including the sources of cells used. Explain the differences between the three prenatal diagnosis techniques. Learn the terms used to describe the Abnormalities in chromosomal numbers: polyploidy, aneuploidy: trisomyand monosomy, and mosiacismand their causing mechanisms.

1 Chromosomes, Karyotyping, and Abnormalities (Learning Objectives) • Learn the components and parts of a metaphase chromosome. • Define the terms karyotype, autosomal and sex chromosomes. Explain how many of each is present in a gamete and in a somatic cell.

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