Transcription of Clinical Pharmacokinetics and Pharmacodynamics
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Clinical Pharmacokinetics and Pharmacodynamics
Clinical Pharmacokineticsand PharmacodynamicsCONCEPTS AND 11/11/09 4:31 PM Page iClinical Pharmacokineticsand PharmacodynamicsConcepts and applications Malcolm Rowland,DSc, PhDProfessor EmeritusSchool of Pharmacy and Pharmaceutical SciencesUniversity of ManchesterManchester, United KingdomFOURTH EDITIONT homas N. Tozer,PharmD, PhDProfessor EmeritusSchool of Pharmacy and Pharmaceutical SciencesUniversity of California, San FranciscoAdjunct Professor of PharmacologySkaggs School of Pharmacy andPharmaceutical SciencesUniversity of California San DiegoWith Online Simulations byHartmut Derendorf, PhDDistinguished ProfessorGuenther Hochhaus, PhDAssociate ProfessorDepartment of PharmaceuticsUniversity of FloridaGainesville, 11/11/09 4:31 PM Page iiiAcquisitions Editor: David B.
sions in mind as our readers. Accordingly, although the principles have wide application, emphasis continues to be at the clinical level. We recognize, however, that pharmacoki-netics and pharmacodynamics are cornerstones in the industrial design, selection, and development of new drugs, and so believe that this textbook is of equal value to ...
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