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Coronary Artery Disease: Pathogenesis, Progression of ...

Lamiaa Mageed*Department of Biochemistry, Egypt*Corresponding author: Lamiaa Mageed, Department of Biochemistry, National Research Center, Giza, EgyptSubmission: July 20, 2018; Published: November 15, 2018 Coronary Artery Disease: Pathogenesis, Progression of Atherosclerosis and Risk FactorsIntroductionCoronary Artery diseaseCoronary Artery diseases (CAD) known as atherosclerotic heart disease, atherosclerotic cardiovascular disease, Coronary heart disease (CHD), or ischemic heart disease (IHD) [1]. CAD is the largest contributor of cardiovascular diseases (CVDs) and mortality rate is due in prevalence to atherosclerosis, a chronic inflammatory condition of the arterial wall. Unfortunately, myocardial infarction (MI) is still a first common manifestation of CHD and, in about 50% of patients; angina pectoris is the first symptom of the pathology [2].

more common in subjects with a sibling or parental history of CHD. ... synergistic mechanism involving inflammation and oxidative stress in the arterial wall [27,28]. ... oxidative stress and increases oxidation of LDL which trigger the . How to cite this article: ...

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