Transcription of Critical Review Report - WHO
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Critical Review Report - WHO
34th ECDD 2006 ketamine Critical Review of KETAMINE Introduction During its meeting in September 2002 the WHO Expert Committee on Drug Dependence did a pre- Review on ketamine (WHO, 2003). Based on the available information a recommendation was given for a Critical Review of this substance. In about the same periode both in The Netherlands (CAM, 2002) as well in The European Union (EMCDDA, 2002) separate Risk Assessment procedures for Ketamine were performed, concluding that there was no need to tighten the current systems for control of this substance, as a pharmaceutical product. The information used in the three abovementioned procedures (meanwhile published) has been the starting point for this Critical Review Report . A Review of pharmacological and toxicological data prepared by Dutch experts (Van Aerts and Van der Laan) has been used (with their permission) for the relevant parts of this Report .
34th ECDD 2006/4.3 ketamine 2. Chemistry Ketamine (2-(2-chlorophenyl)-2-(methylamino)-cyclohexanone) is an arylcycloalkylamine structurally related to phencyclidine (PCP).
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