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Article Brazilian Journal of Pharmaceutical Sciences vol. 47, n. 4, , 2011. Cyclodextrins and ternary complexes : technology to improve solubility of poorly soluble drugs Janisse Crestani de Miranda1, T rcio Elyan Azevedo Martins1, Francisco Veiga2, Humberto Gomes Ferraz1,*. 1. Department of Pharmacy, Faculty of Pharmaceutical Sciences, University of S o Paulo, 2 Faculty of Pharmacy, University of Coimbra Cyclodextrins (CDs) are cyclic oligosaccharides composed of D-glucopyranoside units linked by glycosidic bonds. Their main property is the ability to modify the physicochemical and biological characteristics of low-soluble drugs through the formation of drug:CD inclusion complexes .
Cyclodextrins and ternary complexes: technology to improve solubility of poorly soluble drugs 667 groups can be found at the broadest end, bonded to the
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