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DEPOT PREFILLED DUAL-CHAMBER SYRINGE (PDS) …

Lucrin DEPOT PREFILLED DUAL-CHAMBER SYRINGE (PDS) Injection Version 13 12 May 2015 Page 1 of 18 PRODUCT INFORMATION LUCRIN DEPOT PREFILLED DUAL-CHAMBER SYRINGE (PDS) INJECTION NAME OF THE MEDICINE NON-PROPRIETARY NAME Leuprorelin acetate Chemical Structure CAS Number 53714-56-0 (leuprorelin free peptide) 74381-53-6 (leuprorelin acetate) DESCRIPTION Leuprorelin acetate is a synthetic nonapeptide analogue of naturally occurring gonadotropin releasing hormone (GnRH or LH-RH). The analogue possesses greater potency than the natural hormone. Leuprorelin acetate acts as an inhibitor of gonadotropin production and is chemically unrelated to the steroids.

Lucrin Depot Prefilled Dual-Chamber Syringe (PDS) Injection Version 13 12 May 2015 Page 2 of 18 Lucrin Depot 3-Month PDS Injection is available as sterile lyophilised microspheres, which, when

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