Transcription of Product Information Zyrtec - Medicines
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Product Information Zyrtec - Medicines
Zyrtec PI Page 1 of 8 Australia _____ J&J Pacific 3rd April 2014 1 of 8 Product Information Zyrtec NAME OF THE medicine cetirizine hydrochloride DESCRIPTION cetirizine hydrochloride is an orally active, H1-receptor antagonist. Chemical name: 2-(2-(4-(4-chlorophenyl) phenylmethyl)-1-piperazinyl) ethoxy) acetic acid, dihydrochloride. The molecular weight is and the chemical structure is shown below: CI HC N N CH2 C O C COOH . 2 HCl H2 H2 cetirizine hydrochloride is a white, crystalline powder and is water-soluble (160 g/100 mL). It is formulated as white, film-coated, scored 10 mg tablets, oral liquid 1 mg/mL and oral drops 10 mg/mL. PHARMACOLOGY Mechanism of action: cetirizine , a human metabolite of hydroxyzine, is an antiallergic compound; its principal effects are mediated via competitive occupancy of peripheral H1-receptors.
Zyrtec PI Page 1 of 8 Australia J&J Pacific 3rd April 2014 1 of 8 Product Information Zyrtec NAME OF THE MEDICINE Cetirizine hydrochloride DESCRIPTION Cetirizine hydrochloride is an orally active, H
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